Results 111 to 120 of about 7,945,627 (344)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Rise and fall of the (social) group. [PDF]

Soc Stud Sci, 2022
Armstrong D.
europepmc   +1 more source

Race, Economics, And Social Status [PDF]

, 2018
Social and economic status of an individual or group can be measured as a blend of wealth, income, occupation, and education. Other contributors to social and economic status include race, ethnicity, home ownership, family size, family types, and even ...
Noël, Reginald A
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Labor and professions market for young professionals in the face of economic crisis: challenges and solutions

Высшее образование в России, 2022
The author analyzes the impact of the economic crisis on the labor market for youngprofessionals, which have just graduated from universities. The article asserts the need for state support of this category in job placing.
E. . Kuzmin
doaj  

Social group composition modulates the role of last male sperm precedence in post-copulatory sexual selection. [PDF]

J Evol Biol, 2023
Morimoto J, McDonald GC, Wigby S.
europepmc   +1 more source

Estimating group properties in online social networks with a classifier

, 2018
We consider the problem of obtaining unbiased estimates of group properties in social networks when using a classifier for node labels. Inference for this problem is complicated by two factors: the network is not known and must be crawled, and even high ...
Berry, George, High, Nathan, Kellum, Agrippa, Macy, Michael, Sirianni, Antonio, Weber, Ingmar   +5 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Improving mental ill-health with psycho-social group interventions in South Asia-A scoping review using a realist lens. [PDF]

PLOS Glob Public Health, 2023
Mathias K, Jain S, Fraser R, Davis M, Kimijima-Dennemeyer R, Pillai P, Deshpande SN, Wolters M.   +7 more
europepmc   +1 more source