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Economic and Social History [PDF]
Abstract The last quarter of a century has been one of great changes for the field of early modern economic history. My argument is that, in this period, early modern economic history has shown a remarkably innovative spirit. However, this is most apparent not at the core of the discipline, but in how economic history has interacted with other ...
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Social psychology as history. [PDF]
An analysis of theory and research in social psychology reveals that while methods of research are scientific in character, theories of social behavior are primarily reflections of contemporary history. The dissemination of psychological knowledge modifies the patterns of behavior upon which the knowledge is based.
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Socially reconstructing history: the Social History Timestream application
For centuries, print media controlled by powerful gatekeepers have played a dominant part in the recording and construction of history. Digital media open up new opportunities for the social construction of historical narratives that reveal personal and situated viewpoints.
Fawns, Tim+6 more
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Effects of chronic browsing on life‐history traits of an irruptive large herbivore population
This study aimed to determine the relationship between diet quality, body mass, and size (hind foot length), and female reproduction and sought to identify the mechanism by which high density under severe food limitations is maintained. Our results demonstrated that sika deer introduced to Nakanoshima Island have maintained high densities through high ...
Koichi Kaji+9 more
wiley +1 more source
Dendritic cells steering antigen and leukocyte traffic in lymph nodes
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta+3 more
wiley +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga+6 more
wiley +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source