Results 41 to 50 of about 972,149 (289)

Applying “Knowledge Circulation” in Historical Research

open access: yesÖsterreichische Zeitschrift für Geschichtswissenschaften, 2023
The history of knowledge pays increasing attention to questions of “how, when, and, if necessary, why a certain knowledge emerges – and disappears again”, and further to what effects it has, in which contexts it functions, and who its stakeholders are ...
Lisa Hoppel   +2 more
doaj   +1 more source

Geographic variation in walking activity in the red flour beetle Tribolium castaneum

open access: yesPopulation Ecology, EarlyView.
This study examined whether there is geographic variation in field populations, focusing on the moving activity in the red flour beetle Tribolium castaneum. Results showed significant differences in moving activity among field populations but no correlation with latitude or meteorological factors.
Kentarou Matsumura
wiley   +1 more source

The Left Labourites and the General Strike of 1926 in the UK

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2017
The author analyses the left labourites’ attitude to the interaction of the Labour Party and trade unions and use of general strike as a means of the social struggle. Besides the article analyses the left labourites’ estimation of 1926 general strike and
Evgeniya G. Blosfeld
doaj   +1 more source

occumb: An R package for site occupancy modeling of eDNA metabarcoding data

open access: yesPopulation Ecology, EarlyView.
This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley   +1 more source

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

open access: yesFEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta   +3 more
wiley   +1 more source

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

HYDROLOGICAL LEGACIES OF COLONIALISM: EXAMINING WATER SYSTEMS IN PERLIS, MALAYA (1909–1950)

open access: yesJournal of International Studies, 2023
This study focused on water management and control in Malaya, particularly the establishment of a ‘colonial hydrology’ in Perlis from 1909 to 1950. The study analysed water policies, management techniques, and the social and economic aspects of the ...
DR. Mohd Firdaus Abdullah   +2 more
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

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