Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Practical necessity and the fulfilment of the plan of nature in Kant's idea for a universal history [PDF]
I explore the role of practical necessity in Kant’s essay Idea for a Universal History with a Cosmopolitan Aim. This form of necessity arises on the basis of social and interstate antagonism and Kant appeals to it with the aim of avoiding the ...
James, David Neil
core +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Funcionalidades de la gamificación: Classcraft y Moodle en el marco de Octalysis
La gamificación es una técnica reciente que consiste en aplicar elementos del juego en contextos ajenos al juego. Existen marcos teóricos que sugieren un modelo para aplicar estos elementos en la implementación de soluciones concretas.
Carlos Luis Sánchez-Pacheco
doaj
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Swedish vocational education and training programmes have become increasingly aligned with labour market demands and employability, with consequent risks of marginalisation of citizenship education and formation. Four subjects that have traditionally played important roles in this, history, religious education, science, and social studies, are now only
Katarina Kärnebro +4 more
openaire +2 more sources
La gobernanza como herramienta innovadora para el desarrollo local
Los procesos de desarrollo local que se han iniciado en diferentes países han evidenciado que la actualidad los desafíos de los gobiernos locales son mucho más de articulación de actores y capital social, que de gestión local.
Yalily González Díaz +1 more
doaj +1 more source
Small scale palm oil producers and supply chains left out from existing certification schemes. [ID781] [PDF]
Agricultural history explains most of current palm oil production models (organization of actors including oil palm growers and supply chains). An indigenous non-timber forest product in Central Africa which plant was domesticated and integrated into ...
Durand, Claire +8 more
core
A European perspective on auditory processing disorder-current knowledge and future research focus [PDF]
Current notions of \u201chearing impairment,\u201d as reflected in clinical audiological practice, do not acknowledge the needs of individuals who have normal hearing pure tone sensitivity but who experience auditory processing difficulties in everyday ...
Bamiou, Doris-Eva +22 more
core +7 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source

