Results 81 to 90 of about 2,432,454 (349)

Representations of madness in Indo-Caribbean literature [PDF]

This thesis presents a critical reading of selected Indo-Caribbean prose and poetry and explores their shared concern with issues of madness and insanity.
Gramaglia, Letizia
core  

Structured Psychosocial Stress and Therapeutic Intervention: Toward a Realistic Biological Medicine [PDF]

, 2003
Using generalized 'language of thought' arguments appropriate to interacting cognitive modules, we explore how disease states can interact with medical treatment, including, but not limited to, drug therapy.
Wallace, Rodrick
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Mizaj assessment and data analysis methods in Amirkola health and aging project (AHAP cohort)

Caspian Journal of Internal Medicine, 2022
Background: One of the principles of Persian medicine (PM) is the individualized approach that is presented with the concept of Mizaj. In this viewpoint, Mizaj is determined for every person based on 10 criteria, which is a result of the Mizaj of the ...
Morteza Mojahedi, Roshanak Saghebi, Nargess Gorji, Reihaneh Moeini, Seyed Reza Hosseini, Ali Bijani, Reza Ghadimi, Seyyed Ali Mozaffarpur, Hoda Shirafkan   +8 more
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

East Midlands Research into Ageing Network (EMRAN) Discussion Paper Series [PDF]

, 2019
Academic geriatric medicine in Leicester . There has never been a better time to consider joining us. We have recently appointed a Professor in Geriatric Medicine, alongside Tom Robinson in stroke and Victoria Haunton, who has just joined as a ...
Agarwal, S., Bankart, J., Bannerjee, J., Bell, Katie, Brown, Jayne, Chen, F., Chen, L., Chung, E., Clague-Baker, Nicola, Conroy, Simon, Fallmann, Sarah, Haunton, Victoria, Kondova, D., Larkin, M., Martin, G., Northcott, Andy, O'Kelly, K., Oldridge, Louise, Panerai, R., Phelps, K, Psychoula, I., Raghavan, Raghu, Regen, E., Robinson, T. G., Stahl, Bernd Carsten, 1968-, Subramaniam, H., Triboan, D., Wildbur, D., Williamson, I., Wilson, A.   +29 more
core  

Childhood maltreatment, psychological resources, and depressive symptoms in women with breast cancer. [PDF]

, 2017
Childhood maltreatment is associated with elevated risk for depression across the human lifespan. Identifying the pathways through which childhood maltreatment relates to depressive symptoms may elucidate intervention targets that have the potential to ...
Asher, Arash, Bower, Julienne E, Boyle, Chloe C, Crespi, Catherine M, Ganz, Patricia A, Irwin, Michael R, Kuhlman, Kate Ryan, Petersen, Laura   +7 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

India Giving: Insights into the Nature of Giving Across India [PDF]

, 2012
Giving in India is as ancient as the country itself. The instinct to give is part of the ebb and flow of our daily lives, permeating our religions, our culture and our history.
Richard Harrison, Terrie Maple
core  

Are Large Physiological Reactions to Acute Psychological Stress Always Bad for Health? [PDF]

, 2009
How we react physiologically to stress has long been considered to have implications for our health. There is now persuasive evidence that individuals who show large cardiovascular reactions to stress are at increased risk of developing cardiovascular ...
Acheson, Adolphs, Allen, Al’Absi, Al’Absi, Al’Absi, Anisman, Bachen, Barch, Barnett, Bechara, Beck, Blair, Bosch, Bosch, Bosch, Brydon, Buchanan, Cacioppo, Caldji, Carney, Carroll, Carroll, Carroll, Carroll, Carroll, Carroll, Carroll, Carroll, Caspi, Critchley, Cuthbert, Damasio, Damasio, De Boer, De Boer, Dhabhar, Dhabhar, Ditto, Drummond, Edwards, Edwards, Edwards, Edwards, Enoch, Everson, Everson, Fredrikson, Gagnon, Georgiades, Gianaros, Gianaros, Girdler, Glahn, Goldman, Grassi, Hemingway, Idler, Ishiguro, Kanitz, Kapuku, Kario, Kario, Kibler, Kirschbaum, Kirschbaum, Kirschbaum, Krantz, Lazarus, Leor, Lesch, Light, Lipsky, Liu, Lovallo, Lovallo, Lovallo, Lovallo, Lovallo, Lovallo, Lovallo, Lovallo, Lowe, Lynch, Maier, Manuck, Manuck, Manuck, Manuck, Markovitz, Matthews, Matthews, Meaney, Meaney, Meisel, Mesulam, Millan, Miller, Mischler, Moss, Muldoon, Murdison, Naqvi, Newman, Obrist, Panknin, Patterson, Patterson, Phillips, Phillips, Phillips, Phillips, Phillips, Plotsky, Pomerleau, Rohleder, Rolls, Roy, Schwartz, Sheffield, Silberman, Sims, Smith, Smolka, Sorocco, Straneva, Tentolouris, Tentolouris, Tofler, Treiber, Treiber, Trichopoulos, Tuchscherer, Turner, Ungerleider, Vandenbergh, Welle, Williams, Williams, Witte, Wulsin, York, Zgraggen, Zigmond, Zubieta   +144 more
core   +2 more sources