Results 141 to 150 of about 794,878 (303)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Social responsibility, organisational support, and identification: An approach to non-profit organisations [PDF]

open access: yes
In an era where social responsibility is increasingly embedded in organisational strategy, this study scrutinises the infusion of social responsibility into the strategic underpinnings of non-profit organisations.
Santos, G., Justino, E.
core   +1 more source

Pharmacy student professional identity formation: a scoping review

open access: yesIntegrated Pharmacy Research and Practice, 2019
Christy Noble,1–3 Leigh McKauge,3 Alexandra Clavarino3 1Allied Health, Clinical Governance, Education and Research, Gold Coast Health, Southport, QLD, Australia; 2School of Medicine, Griffith University, Parkwood, QLD, Australia; 3School of ...
Noble C, McKauge L, Clavarino A
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

British Social Attitudes Survey, 2017

open access: yes, 2019
copyright UK Data Service and data collection copyright owner.BackgroundThe British Social Attitudes (BSA) survey series began in 1983. The series is designed to produce annual measures of attitudinal movements to complement large-scale government ...
NatCen Social Research
core  

Editorial: Multiple Identities Management: Effects on (of) Identification, Attitudes, Behavior and Well-Being

open access: yesFrontiers in Psychology, 2017
Clara Kulich   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Identidades profissionais médicas em disputa: Congresso Nacional dos Práticos, Brasil (1922)

open access: yesCadernos de Saúde Pública
O objeto deste artigo é o debate travado entre a elite médica brasileira durante o Congresso Nacional dos Práticos, realizado no Rio de Janeiro em 1922. Inicialmente apresentamos o conceito profissão do ponto de vista sociológico.
André de F. Pereira Neto
doaj  

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