Results 121 to 130 of about 737,776 (266)

Identity Framing as Resilience in Selected Nicknames of Nigerian Street Children

Languages
Street children who are forced onto the streets due to oppressive experiences use a variety of strategies, including nicknaming, to cope with street adversities.
Ezekiel Opeyemi Olajimbiti
doaj   +1 more source

Reclaiming Sacred Space [PDF]

, 2019
I wrote this piece for myself as a hybrid of personal discovery and academic inquiry, and I hope it can guide and empower others like myself. In this piece, I examine the intersections of queer identity with religious and spiritual identity development ...
Long, Patrick Griffin
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Tools for assessing professional identity in health professions education: A scoping review

Journal of Medical Ethics and History of Medicine
Due to the complexity and multidimensional nature of professional identity assessment in health professions education, it is essential to establish appropriate criteria.
Zahra Sadat Tabatabaei, Homaun Amini, Mahboobeh Khabaz Mafinejad   +2 more
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Jarmila Mildorf, Life Storying in Oral History. Fictional Contamination and Literary Complexity

European Journal of Life Writing
In Life Storying in Oral History. Fictional Contamination and Literary Complexity (2023), Jarmila Mildorf examines oral storytelling as a complex rhetorical enterprise.
Zuzana Fonioková
doaj   +1 more source

\u3ci\u3eDemocracy\u27s Discontent\u3c/i\u3e in a Complex World: Can Avalanches, Sandpiles, and Finches Optimize Michael Sandel\u27s Civic Republican Community? [PDF]

, 1997
In Democracy\u27s Discontent: America in Search of a Public Philosophy, Michael Sandel looks about him and finds a vast and complex world governed by impersonal institutions and structures, in which discontented, anxious, and frustrated individuals are ...
Babcock, Hope M.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Representation of Kimberle Crenshaw’s intersectionality in the novel Rara Mendut by Y. B. Mangunwijaya

Studies in English Language and Education
Intersectionality studies are gaining increasing attention in the humanities and literary research, especially in the context of feminist literary analysis and gender studies. This research aimed to describe the representation of intersectionality in the
Sri Lestari, Retno Winarni, Sumarwati Sumarwati   +2 more
doaj   +1 more source