Results 51 to 60 of about 333,273 (265)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Borders in Globalization Review, 2022 Drawing on visual studies, this mixed-media portfolio explores the mixed culture of the US–Mexico border. Emerging around the turn of the millennium as a multidisciplinary study from such diverse fields as art history, aesthetics, film theory, cultural studies, media theory, visual culture, postcolonial studies, and gender studies, visual studies ...
openaire +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Non‐concept density estimation via kernel regression for concept ranking in weakly labelled data
IET Computer Vision, 2018 Automatic object annotation for weakly labelled images/videos has attracted great research interests. In the literature, the idea of negative mining has been proposed for the task.
Liantao Wang +3 more
doaj +1 more source
Image of social studies at Google [PDF]
, 2012 Social Studies Course is a lecture that ensures the students to recognize their society and the world, to involve into the social life actively towards the solution of the problems they have faced with in this respect. However, the researches indicate that this course is one of the least favorite courses by the students.
Öztürk, Cemil +2 more
openaire +1 more source
Who Cares for Social Image? Interactions between Intrinsic Motivation and Social Image Concerns [PDF]
SSRN Electronic Journal, 2013 We consider the interaction of intrinsic motivation and concerns for social approval in a laboratory experiment. We elicit a proxy for Fairtrade preferences before the experiment. In the experiment, we elicit willingness to pay for conventional and Fairtrade chocolate. Treatments vary whether this can be signalled to other participants.
Jana Friedrichsen, Dirk Engelmann
openaire +5 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
What’s moral wiggle room? A theory specification
Judgment and Decision MakingThe term ‘moral wiggle room’ (MWR) is often used to describe features of social situations that reduce the transparency between behaviors and their consequences. Previous research found that MWR decreases the likelihood of prosocial behavior and inferred
Alina Fahrenwaldt +3 more
doaj +1 more source
AI bias in lung cancer radiotherapy [PDF]
Exploration of Digital Health TechnologiesAim: In lung cancer research, AI has been trained to read chest radiographs, which has led to improved health outcomes. However, the use of AI in healthcare settings is not without its own set of drawbacks, with bias being primary among them.
Kai Ding +5 more
doaj +1 more source