Results 111 to 120 of about 2,252,232 (307)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
A multidimensional assessment of social cohesion in 47 European countries [PDF]
This paper presents a theoretically based, multidimensional and comparable measurementof social cohesion applicable in 47 European countries using the most recent micro-level data of European Value Study (EVS) from 2008. The analysis is conducted in four
BORSENBERGER Monique +2 more
core +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Monitoring Economic and Social Changes within NSW Water Sharing Plan Areas: A Participatory Approach [PDF]
This paper presents a participatory approach being used to monitor the changes in economic and social indicators within the Water Sharing Plan areas in NSW.
Bari, Maksudul +2 more
core +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Mapping Varieties of Industrial Relations: Eurofound\u27s Analytical Framework Applied [PDF]
, 2017 Eurofound’s 2016 report Mapping key dimensions of industrial relations identified four key dimensions of industrial relations: industrial democracy, industrial competitiveness, social justice, and quality of work and employment.
Caprile, Maria +4 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Tracking Oregon's Progress: A Report of the Tracking Oregon's Progress (TOP) Indicators Project [PDF]
, 2014 In 1989, Oregon embarked on a novel experiment to track the progress of the state toward a set of economic, social and environmental goals embodied in the state strategic plan Oregon Shines.
Bruce Weber +3 more
core
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Trabalho, precarização e resistências: novos e velhos desafios?
Caderno CRHO artigo discute por que a precarização social do trabalho é um novo e velho fenômeno, é diferente e igual, é passado e presente, um fenômeno de caráter macro e microssocial.
Graça Druck
doaj +1 more source