Results 121 to 130 of about 2,252,232 (307)

Economic, Social, and Environmental Benefits Associated With U.S. Organic Agriculture [PDF]

open access: yes, 2005
This case study reviews the economic, social, and environmental benefits associated with organic agriculture in the United States. Measurable impacts are quantified by comparing indicators of benefits in counties with organic farms and counties without ...
Lohr, Luanne
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Magnetizing Neighborhoods Through Amateur Arts Performance [PDF]

open access: yes, 2008
Outlines the Arts and Cultural Indicators in Community Building Project's findings on how amateur, informal arts activity improves a community's desirability, social integration, and quality of life as measured by population, test scores, and crime ...
D. Garth Taylor
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

The Scorecard on Development: 25 Years of Diminished Progress [PDF]

open access: yes
This paper examines data on economic growth and various social indicators and compares the past 25 years (1980-2005) with the prior two decades (1960-1980).
David Rosnick, Dean Baker, Mark Weisbrot
core  

Welfare state and social spending: assessing the effectiveness and the efficiency of European social policies in 22 EU countries [PDF]

open access: yes, 2018
This paper aims at analysing the effectiveness and the efficiency of social public expenditure in 22 European countries. We present a basic theoretical framework connecting the choice of the level of social protection to the median voter’s preferences ...
Antonelli, MARIA ALESSANDRA   +1 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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