Results 121 to 130 of about 2,264,677 (307)
Trends in social indicators and social sector financing [PDF]
Over the past three decades, per capita GDP has increased worldwide. The authors examine whether this has resulted in better quality of life in developing countries.
Englebert, Pierre +2 more
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Economic, Social, and Environmental Benefits Associated With U.S. Organic Agriculture [PDF]
, 2005 This case study reviews the economic, social, and environmental benefits associated with organic agriculture in the United States. Measurable impacts are quantified by comparing indicators of benefits in counties with organic farms and counties without ...
Lohr, Luanne
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
The Scorecard on Development: 25 Years of Diminished Progress [PDF]
This paper examines data on economic growth and various social indicators and compares the past 25 years (1980-2005) with the prior two decades (1960-1980).
David Rosnick, Dean Baker, Mark Weisbrot
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Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
'A disastrous blow': psychiatric risk, social indicators and medical authority in abortion reform in post-war Britain. [PDF]
Med Humanit, 2020 Crook S.
europepmc +1 more source
Tracking Oregon's Progress: A Report of the Tracking Oregon's Progress (TOP) Indicators Project [PDF]
, 2014 In 1989, Oregon embarked on a novel experiment to track the progress of the state toward a set of economic, social and environmental goals embodied in the state strategic plan Oregon Shines.
Bruce Weber +3 more
core
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source