Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Using the Stressor-System-Resilience Resources-Outcomes (SSRO) scaffold to clarify the core components of resilience research in medicine. [PDF]
Ravi DK, Koivunen K, Bos KD, Melis RJ.
europepmc +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Medication Literacy and Social Support Among Adult Liver Transplant Recipients: A Cross-Sectional Study. [PDF]
Niu H +6 more
europepmc +1 more source
Social support ecosystems for adolescent physical activity: a mixed-methods evaluation framework and empirical evidence from China. [PDF]
Luo H, Chen Z.
europepmc +1 more source
Social vulnerability and psychological resources in aging: the role of index weighting and attrition bias. [PDF]
Saberi K +4 more
europepmc +1 more source
Breakthrough in architecture-Contemporary Iraqi architecture case study. [PDF]
Al-Assadi FI +2 more
europepmc +1 more source
COMPOUNDING ASSOCIATIONS OF EDUCATION AND SOCIAL CARE SUPPORT ON HOSPITAL COSTS THROUGHOUT CHILDHOOD
Lau Y, Gilbert R, Pulido G, Sutton M.
europepmc +1 more source
The Human Flourishing Geographic Index: A County-Level Dataset for the United States, 2013-2023. [PDF]
Iacus SM +5 more
europepmc +1 more source

