ESTADO ACTUAL DE LOS DERECHOS A LA IDENTIDAD, A LA VIDA Y LA VIVIENDA EN LA POBLACIÓN EN VÍCTIMA DEL DESPLAZAMIENTO FORZADO EN ANTIOQUIA.(CURRENT STATE OF THE RIGHTS TO IDENTITY, TO LIFE, AND TO HOUSING, IN THE POPULATION VICTIM OF FORCED DISPLACEMENT IN ANTIOQUIA) [PDF]
El Ágora USB, 2011 El siguiente artículo es un informe de investigación que expone el diseño metodológico de una serie de indicadores que permiten establecer el estado del Goce Efectivo de Derechos (GED) de la población en situación de desplazamiento en el departamento de ...
NICOLAS ESPINOSA MENDEZ +3 more
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Eurasian Journal of Economic and Business StudiesThis study presents a comprehensive analysis of the development dynamics of cities in Kazakhstan, focusing on the interplay between economic and social factors and their impact on the Gross Regional Product (GRP). Employing a dataset encompassing a range
Maxat Shakibayev +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
FACTORES DE RIESGO PARA EL DESPLAZAMIENTO, PROTECCIÓN DE TIERRAS Y GARANTÍAS DE NO REPETICIÓN EN ZONAS VULNERABLES DE ANTIOQUIA. SOCIO-DEMOGRAPHIC PROFILE OF DISPLACED POPULATION IN ANTIOQUIA [PDF]
El Ágora USB, 2012 El siguiente artículo es un informe de investigación que recoge apartes del documento sobre el estado actual del Goce Efectivo de Derechos de la población víctima del desplazamiento Forzado en Antioquia.
Juan Esteban Monsalve Rojas +3 more
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Questão social em Portugal: indicadores e desafios para o Serviço Social
EleutheraObjective. Present a preliminary study of Portugal’s expressions of the social question, emphasizing its integration into the European Union and the analysis of indicators for monitoring the risk of poverty (EAPN, 2023).
Alexandra Aparecida Leite Toffanetto Seabra Eiras +3 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source