Results 61 to 70 of about 477,384 (301)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Frontiers in Public HealthBackgroundType D personality is characterized by negative affect (NA) and social suppression (SI). It has been indicated Type D personality is associated with depression, anxiety, and burnout. Depressive complaints and social inhibition negatively affect
Ayşegül Yetkin Tekin, Hekim Karadağ
doaj +1 more source
Resting frontal asymmetry and reward sensitivity theory motivational traits [PDF]
, 2018 The revised reinforcement sensitivity theory (rRST) of personality has conceptualized three main systems: the behavioural approach system (BAS), behavioural inhibition system (BIS), and fightflight- freeze system (FFFS). Research links greater relative
De Pascalis, Vilfredo +2 more
core +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Pdxdc1 modulates prepulse inhibition of acoustic startle in the mouse. [PDF]
, 2017 Current antipsychotic medications used to treat schizophrenia all target the dopamine D2 receptor. Although these drugs have serious side effects and limited efficacy, no novel molecular targets for schizophrenia treatment have been successfully ...
Boutros, PC +5 more
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Type D personality is associated with hyperlipidemia in patients with myocardial infarction
Journal of Research in Medical Sciences, 2012 Objective: There are many studies indicating the role of psychological factors in the pathogenesis of cardiovascular disorders. Type D as a new personality construct has been proposed by Denollet, characterized by the joint global traits including ...
Reza Bagherian-Sararoudi +3 more
doaj
Design and Testing a Model of Some Antecedents of students Social Anxiety [PDF]
مطالعات روانشناختیThe aim of this study was to design and test a model of some antecedents of social anxiety. This descriptive research used the structural equation modeling (SEM) method.
Mahdi Hassanvand Amouzadeh
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The Role of Microglial CX3CR1 in Schizophrenia-Related Behaviors Induced by Social Isolation
Frontiers in Integrative Neuroscience, 2020 According to the microglial hypothesis of schizophrenia, the hyperactivation of microglia and the release of proinflammatory cytokines lead to neuronal loss, which is highly related to the onset of schizophrenia.
Hao Zhou +4 more
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Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source