Results 61 to 70 of about 1,062,305 (293)

Social Innovations as a Contribution to Strengthening Social Cohesion and Mitigating Social Crisis in European Urban Social Programs [PDF]

open access: yes, 2016
U radu se razmatra potencijalni doprinos socijalnih inovacija jačanju socijalne kohezije i ublažavanju učinaka krize. U politikama i programima financiranja Europske unije socijalne inovacije prepoznaju se kao važan doprinos jačanju socijalne kohezije ...
Danijel Baturina   +2 more
core   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Theoretical foundations of research on popular legal culture among students of pedagogy, social work and teachers - research and application perspective [PDF]

open access: yesStudia z Teorii Wychowania
The text is the first in a series of studies on popular legal culture. The research is carried out as part of a grant from the Innovation Leaders Academy pilot program.
Dagna Dejna   +1 more
doaj   +1 more source

A Meta-Analysis of Alternative Water Sources [PDF]

open access: yes, 2012
Roughly one half of the Earth’s population suffers from shortage or lack of clean water. While many innovations and products have been created to address this Global Water Crisis, no comparisons have been done as to which innovations and products are the
Colton, Katie
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

PROMOTING SOCIAL INNOVATION USING MARKETING AND COMMUNICATION TOOLS [PDF]

open access: yesAnnals of the University of Craiova: Economic Sciences Series, 2019
The complexity of social problems involves sustained interventions not only from state actors but also from non-profit organizations. These initiators are called upon to address various issues, of a large group of beneficiaries, in the most creative way ...
Cătălin Mihail Barbu   +2 more
doaj  

A Social Enterprise Within the Meaning of the Social Economy Act in the Context of Economic Theory and Practice

open access: yesStudia Ekonomiczne i Regionalne, 2022
Subject and purpose of work: This study explores the characteristics of a social enterprise as laid down in the relevant act currently in force, and analyzes how the tendencies to normatively define a social enterprise have changed over the years with ...
Brdulak Jacek, Florczak Ewelina
doaj   +1 more source

Diffusion of innovations in social networks [PDF]

open access: yes, 2011
While social networks do affect diffusion of innovations, the exact nature of these effects are far from clear, and, in many cases, there exist conflicting hypotheses among researchers.
Acemoglu, Daron   +2 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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