Results 61 to 70 of about 12,253,362 (313)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

THE FORMATION OF INNOVATION COMPETENCE OF FUTURE SOCIAL SPHERE SPECIALIST

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки, 2017
The transformations, occurring in the social sphere of Russia are analyzed. At the modern stage the transition from stagnancy in the social sphere to the development, this period is characterized by the implementation of innovative technologies of social
A. A. Druzhinina
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

AssetsAfrica

open access: yes, 2017
AssetsAfrica, implemented from 2004 to 2008, was a demonstration and research initiative designed to test asset building innovations and their impact on household asset accumulation and well-being in rural Africa.
Global Social Development Innovations
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

'Invited Talk' Case Studies of solving social issues using ICT in the Asia Pacific Region

open access: yes, 2023
With the support of the Ministry of Internal Affairs and Communications of Japan (MC), and Asia-Pacific Telecommunity (APT) the Telecommunication Technology Committee (TTC) has been conducting case studies using ICT to solve social issues in ...
Institute of Social Informatics and Technological Innovations, Universiti Malaysia Sarawak
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Social Innovations in the Urban Context [PDF]

open access: yes, 2016
This book addresses the practice of social innovation, which is currently very much in the public eye. New ideas and approaches are needed to tackle the severe and wicked problems with which contemporary societies are struggling. Especially in times of economic crisis, social innovation is regarded as one of the crucial elements needed to move forward.
Brandsen, Taco (Ed.)   +3 more
openaire   +5 more sources

Theoretical foundations of research on popular legal culture among students of pedagogy, social work and teachers - research and application perspective [PDF]

open access: yesStudia z Teorii Wychowania
The text is the first in a series of studies on popular legal culture. The research is carried out as part of a grant from the Innovation Leaders Academy pilot program.
Dagna Dejna   +1 more
doaj   +1 more source

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