Results 31 to 40 of about 284,909 (155)

No inflammatory effects after acute inhalation of barium sulfate particles in human volunteers

BMC Pulmonary Medicine, 2022
Background Most threshold limit values are based on animal experiments. Often, the question remains whether these data reflect the situation in humans. As part of a series of investigations in our exposure lab, this study investigates whether the results
Christian Monsé, Götz Westphal, Monika Raulf, Birger Jettkant, Vera van Kampen, Benjamin Kendzia, Leonie Schürmeyer, Christoph Edzard Seifert, Eike-Maximilian Marek, Felicitas Wiegand, Nina Rosenkranz, Christopher Wegener, Rolf Merget, Thomas Brüning, Jürgen Bünger   +14 more
doaj   +1 more source

Effects of wearing different face masks on cardiopulmonary performance at rest and exercise in a partially double-blinded randomized cross-over study

Scientific Reports, 2023
The use of face masks became mandatory during SARS-CoV-2 pandemic. Wearing masks may lead to complaints about laboured breathing and stress. The influence of different masks on cardiopulmonary performance was investigated in a partially double-blinded ...
Eike-Maximillian Marek, Vera van Kampen, Birger Jettkant, Benjamin Kendzia, Bianca Strauß, Kirsten Sucker, Melanie Ulbrich, Anja Deckert, Hans Berresheim, Christian Eisenhawer, Frank Hoffmeyer, Simon Weidhaas, Thomas Behrens, Thomas Brüning, Jürgen Bünger   +14 more
doaj   +1 more source

Biomonitoring of polycyclic aromatic hydrocarbons in firefighters at fire training facilities and in employees at respiratory protection and hose workshops

Frontiers in Public Health, 2023
IntroductionPolycyclic aromatic hydrocarbons (PAHs) are carcinogenic to humans and are formed by incomplete combustion. PAHs are always present during firefighting operations, and fire department members can be exposed to them in the workplace.MethodsIn ...
Stephan Koslitz, Birgit Heinrich, Heiko U. Käfferlein, Holger M. Koch, Tim Pelzl, Katrin Pitzke, Daniel Köster, Tobias Weiß, Volker Harth, Thomas Brüning, Thomas Behrens, Dirk Taeger   +11 more
doaj   +1 more source

Second-line pharmacotherapy intensification after metformin monotherapy in type 2 diabetes: a nationwide register study from Finland during 2011–2022

BMC Health Services Research
Background In this nationwide register study, we examined the initiation of a second-line antidiabetic medicine (ADM) among new patients receiving regular metformin monotherapy in Finland during 2011–2022.
Hanna Rättö, Terhi Kurko, Pia Pajunen, Helena Kastarinen   +3 more
doaj   +1 more source

Occupational-class trends in diagnosis-specific sickness absence in Finland: a register-based observational study in 2011–2021

BMJ Open
Objectives To examine the prevalence and days of long-term sickness absence (LTSA) by occupational class and by most important diagnostic groups in Finland during 2011–2021.Design Population-based cross-sectional study.Setting and participants National ...
Jenni Blomgren, Riku Perhoniemi
doaj   +1 more source

Prescribing patterns before the initiation of novel antidiabetic medicines in public, occupational, and private healthcare: a register study reflecting the guidelines of care in type 2 diabetes

BMC Health Services Research
Background Disparities in access to healthcare has been implied before in Finland, a country with universal healthcare but de facto tiered primary care. Less is however known about the content of care provided in different settings.
Hanna Rättö, Mikko Nurminen, Katri Aaltonen   +2 more
doaj   +1 more source

New cancer medicines in Europe 2010–2020: comparison of medicines with or without extensions of indications

BMJ Open
Introduction During the last decade, extensions of therapeutic indications have been one of the most common methods to extend the lifecycle of a medical product in the post-authorisation phase and to increase the use and sales of medicines.
Kati Sarnola, Hanna Koskinen, Anna-Maria Ruuskanen, Terhi Kurko, Katariina Klintrup   +4 more
doaj   +1 more source

Long-term sickness absences based on mental disorders by socioeconomic group – trends of prevalence in Finland 2010–2023

BMC Public Health
Background Long-term sickness absences (LTSA) are often linked to mental disorders. Up-to-date register-based evidence on the prevalence and trends of LTSA based on mental disorders is lacking, as is understanding of socioeconomic differences. This study
Riku Perhoniemi, Jenni Blomgren
doaj   +1 more source

Assessment of Confounding Factors Affecting the Tumor Markers SMRP, CA125, and CYFRA21-1 in Serum

Biomarker Insights, 2010
The purpose of this analysis was to evaluate if serum levels of potential tumor markers for the diagnosis of malignant mesothelioma and lung cancer are affected by confounding factors in a surveillance cohort of workers formerly exposed to asbestos. SMRP,
Daniel Gilbert Weber, Georg Johnen, Dirk Taeger, Anne Weber, Isabelle Mercedes Gross, Beate Pesch, Thomas Kraus, Thomas Brüning, Monika Gube   +8 more
doaj   +1 more source

Non-dispensed prescriptions – A nationwide descriptive study

Exploratory Research in Clinical and Social Pharmacy
Background: Medication non-adherence is associated with suboptimal health outcomes, higher mortality, and increased healthcare costs. Objective: The aim of this study was to estimate the number and share of non-dispensed prescriptions at a national level
Heini Kari, Fredriikka Nurminen, Hanna Rättö, Hanna Koskinen   +3 more
doaj   +1 more source