Results 21 to 30 of about 1,519,876 (263)

No inflammatory effects after acute inhalation of barium sulfate particles in human volunteers

BMC Pulmonary Medicine, 2022
Background Most threshold limit values are based on animal experiments. Often, the question remains whether these data reflect the situation in humans. As part of a series of investigations in our exposure lab, this study investigates whether the results
Christian Monsé, Götz Westphal, Monika Raulf, Birger Jettkant, Vera van Kampen, Benjamin Kendzia, Leonie Schürmeyer, Christoph Edzard Seifert, Eike-Maximilian Marek, Felicitas Wiegand, Nina Rosenkranz, Christopher Wegener, Rolf Merget, Thomas Brüning, Jürgen Bünger   +14 more
doaj   +1 more source

New cancer medicines in Europe 2010–2020: comparison of medicines with or without extensions of indications

BMJ Open
Introduction During the last decade, extensions of therapeutic indications have been one of the most common methods to extend the lifecycle of a medical product in the post-authorisation phase and to increase the use and sales of medicines.
Kati Sarnola, Hanna Koskinen, Anna-Maria Ruuskanen, Terhi Kurko, Katariina Klintrup   +4 more
doaj   +1 more source

Biomonitoring of polycyclic aromatic hydrocarbons in firefighters at fire training facilities and in employees at respiratory protection and hose workshops

Frontiers in Public Health, 2023
IntroductionPolycyclic aromatic hydrocarbons (PAHs) are carcinogenic to humans and are formed by incomplete combustion. PAHs are always present during firefighting operations, and fire department members can be exposed to them in the workplace.MethodsIn ...
Stephan Koslitz, Birgit Heinrich, Heiko U. Käfferlein, Holger M. Koch, Tim Pelzl, Katrin Pitzke, Daniel Köster, Tobias Weiß, Volker Harth, Thomas Brüning, Thomas Behrens, Dirk Taeger   +11 more
doaj   +1 more source

Occupational-class trends in diagnosis-specific sickness absence in Finland: a register-based observational study in 2011–2021

BMJ Open
Objectives To examine the prevalence and days of long-term sickness absence (LTSA) by occupational class and by most important diagnostic groups in Finland during 2011–2021.Design Population-based cross-sectional study.Setting and participants National ...
Jenni Blomgren, Riku Perhoniemi
doaj   +1 more source

Optimal Taxation and Social Insurance ina Lifetime Perspective [PDF]

Advances in information technology have improved the administrative feasibility ofredistribution based on lifetime earnings recorded at the time of retirement.
Lans Bovenberg, Peter Birch Sørensen
core   +6 more sources

Second-line pharmacotherapy intensification after metformin monotherapy in type 2 diabetes: a nationwide register study from Finland during 2011–2022

BMC Health Services Research
Background In this nationwide register study, we examined the initiation of a second-line antidiabetic medicine (ADM) among new patients receiving regular metformin monotherapy in Finland during 2011–2022.
Hanna Rättö, Terhi Kurko, Pia Pajunen, Helena Kastarinen   +3 more
doaj   +1 more source

Patient Activation in Childhood, Adolescent, and Young Adult Cancer Survivors: Current Insights and Implications for Survivorship Care—A Systematic Review From the e‐QuoL Project

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Patient activation—encompassing knowledge, confidence, and skills in managing individual's health—is a cornerstone of person‐centered care. However, its significance among childhood, adolescent, and young adult cancer survivors (CAYACS) remains unexplored. This article examines the application of the 13‐item Patient Activation Measure (
Charlotte Demoor‐Goldschmidt, Anne Maas, Gisela Michel, Amandine Bertrand, Kristen E. T. Thornton, Martine Bellanger, Anna‐Liesa Filbert, Desiree Grabow, Monica Muraca, Katharina Roser, Sara Oberti, Jelena Roganovic, Hanne Cathrine Lie   +12 more
wiley   +1 more source

Prescribing patterns before the initiation of novel antidiabetic medicines in public, occupational, and private healthcare: a register study reflecting the guidelines of care in type 2 diabetes

BMC Health Services Research
Background Disparities in access to healthcare has been implied before in Finland, a country with universal healthcare but de facto tiered primary care. Less is however known about the content of care provided in different settings.
Hanna Rättö, Mikko Nurminen, Katri Aaltonen   +2 more
doaj   +1 more source

Utility of Computed Tomography Surveillance of Asymptomatic Infection in Children and Young Adults Before Allogeneic Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Asymptomatic infection poses a significant risk for children undergoing hematopoietic stem cell transplantation (HSCT). Pre‐transplant surveillance computed tomography (CT) is commonly used to identify occult infection, though its diagnostic yield remains uncertain.
Tyler Obermark, Pradipta Debnath, Rama S. Ayyala, Lara A. Danziger‐Isakov, Jane Koo, Kasiani C. Myers, William R. Otto, Aki Tanimoto, Andrew T. Trout, Cara E. Morin   +9 more
wiley   +1 more source

Unheard and Under‐Supported: Health‐Related Quality of Life in Children, Adolescents, and Young Adults With Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
Abstract Background Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy affecting millions of individuals worldwide. The clinical expression and psychosocial burden of SCD vary widely across geographical, cultural, and healthcare system contexts, underscoring the need for setting‐specific approaches to assessment.
Desiré Fantasia, Giulia Reggiani, Elizabeth J. Maran, Maria Elisa Delle Fave, Ilaria Baido, Anna Chiara Frigo, Maria Paola Boaro, Raffaella Colombatti   +7 more
wiley   +1 more source