Results 61 to 70 of about 870,885 (308)

The Switching of Trailing Limb Anticipatory Locomotor Adjustments is Uninfluenced by what the Leading Limb Does, but General Time Constraints Remain

open access: yesApplied Sciences, 2020
Research shows a blend of bilateral influence and independence between leading and trailing limbs during obstacle avoidance. Recent research also shows time constraints in switching leading limb strategies.
Félix Fiset, Bradford J. McFadyen
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

In the Mix: Social Integration and Social Media Adoption

open access: yesSocial Science Research, 2019
What is the nature of the relationship between online and offline social life? Specifically, how does participation in the traditional forms of social life of a community shape social media adoption? Using a unique, two-wave panel dataset with saturated network data from over 20,000 students in 56 New Jersey middle schools, we test how measures of ...
Shepherd, Hana, Lane, Jeffrey
openaire   +4 more sources

The merry-go-round of disadvantage: educational policy and integration in segregated schools

open access: yes, 2008
Segregated schools are associated with problems. Educational disadvantage among pupils at these schools persists and these kinds of schools, more than other kinds of schools, are confronted the most with societal problems.
Social Policy, Interventions and Integration   +2 more
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Institute on Community Integration Annual Report: 2010-11

open access: yes, 2011
The annual report summarizing the work and community impact of the Institute on Community Integration, a federally–designated University Center for Excellence in Developmental Disabilities working to improve community services and social supports for ...
Institute on Community Integration
core  

Social integration: approaches and issues

open access: yes, 1995
The World Summit for Social Development, to be held in Copenhagen in March 1995, will consider three closely inter-related themes: decreasing poverty, reducing unemployment, and enhancing social integration.
Hewitt de Alcántara, Cynthia
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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