Results 61 to 70 of about 15,794,740 (302)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Switching of Trailing Limb Anticipatory Locomotor Adjustments is Uninfluenced by what the Leading Limb Does, but General Time Constraints Remain

open access: yesApplied Sciences, 2020
Research shows a blend of bilateral influence and independence between leading and trailing limbs during obstacle avoidance. Recent research also shows time constraints in switching leading limb strategies.
Félix Fiset, Bradford J. McFadyen
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

What future for the European social model? The relevance of early intellectual concepts of social integration [PDF]

open access: yes, 2020
The classic account of European social integration starts with the near-exclusion of European social policy from the European Economic Community Treaty (1957). The final version of the Treaty reflected a consensus which relied on market forces for growth
Zahn, Rebecca
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

In the Mix: Social Integration and Social Media Adoption

open access: yesSocial Science Research, 2019
What is the nature of the relationship between online and offline social life? Specifically, how does participation in the traditional forms of social life of a community shape social media adoption? Using a unique, two-wave panel dataset with saturated network data from over 20,000 students in 56 New Jersey middle schools, we test how measures of ...
Shepherd, Hana, Lane, Jeffrey
openaire   +4 more sources

Institute on Community Integration Annual Report: 2009-10

open access: yes, 2010
The annual report summarizing the work and community impact of the Institute on Community Integration, a federally–designated University Center for Excellence in Developmental Disabilities working to improve community services and social supports for ...
Institute on Community Integration
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Institute on Community Integration Annual Report: 2010-11

open access: yes, 2011
The annual report summarizing the work and community impact of the Institute on Community Integration, a federally–designated University Center for Excellence in Developmental Disabilities working to improve community services and social supports for ...
Institute on Community Integration
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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