Results 111 to 120 of about 14,861,156 (315)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Street Puppet Theatre Shows on the Façades of Commercial Buildings as a Novel Stimulator for Social Gatherings in Smart Cities

open access: yesBuildings
This study investigates the innovative use of street puppet theatre performances on the façades of commercial buildings to stimulate social gatherings in smart cities.
Reza Askarizad   +2 more
doaj   +1 more source

When is social media use social interaction? Defining mediated social interaction [PDF]

open access: yesNew Media & Society, 2016
This investigation explores the question, when is social media use social interaction? The results of three studies indicated that social media use was rarely considered social interaction. After using social media for 5 or 10 minutes, Study 1 ( N = 116) demonstrated that infrequent, directed social media behavior (e.g.
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Interacciones sociales en el patio de recreo que tienen el potencial de apoyar el aprendizaje del concepto de probabilidad

open access: yesRevista Latinoamericana de Etnomatemática, 2015
This research analyzes the social interactions of students at the playground, in order to establish relationships between school and extracurricular knowledge through the elaboration of mathematical projections of the concept of probability.
Arley Zamir Chaparro, José Leguizamón
doaj  

Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function

open access: yesCell Reports, 2016
Human haploinsufficiency of the transcription factor Tcf4 leads to a rare autism spectrum disorder called Pitt-Hopkins syndrome (PTHS), which is associated with severe language impairment and development delay.
Andrew J. Kennedy   +17 more
doaj   +1 more source

Local Interactions [PDF]

open access: yes
Local interactions refer to social and economic phenomena where individuals' choices are influenced by the choices of others who are `close' to them socially or geographically. This represents a fairly accurate picture of human experience.
Onur Özgür
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Strategic Planning of Public Spaces in Order to Promote and Benefit from Social Interactions, Case Study: District 10 of Tehran Municipality [PDF]

open access: yesتحقیقات کاربردی علوم جغرافیایی
Public spaces and social interactions have a reciprocal relationship. The rapid urbanization, limited land availability, and neglect of these spaces in urban development initiatives have resulted in a scarcity of open and green areas per capita ...
samaneh jalilisadrabad   +1 more
doaj  

Does the relationship between affect and social interactions among adults experiencing homelessness differ during moments when at a shelter versus not?

open access: yesMental Health Science
The prevalence of alcohol‐use disorders is higher amongst adults experiencing homelessness (AEH) compared with domiciled adults. Greater exposure to heavy drinkers increases personal risk for heavy alcohol use.
Jamie M. Gajos   +4 more
doaj   +1 more source

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