Results 41 to 50 of about 689,448 (268)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A method for detecting characteristic patterns in social interactions with an application to handover interactions [PDF]

open access: yesRoyal Society Open Science, 2017
Social interactions are a defining behavioural trait of social animals. Discovering characteristic patterns in the display of such behaviour is one of the fundamental endeavours in behavioural biology and psychology, as this promises to facilitate the ...
Nikolai W. F. Bode   +4 more
doaj   +1 more source

Social Capital of Impoverished Students: A Study on the Strength of Social Networks, Trust, and Norms among Impoverished Students

open access: yesSociety, 2023
This study examines the social capital of impoverished students who possess limited economic resources. To thrive in school, these students heavily rely on strong social capital.
Nanang Martono   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Toward a Neuroscientific Understanding of Play: A Dimensional Coding Framework for Analyzing Infant–Adult Play Patterns

open access: yesFrontiers in Psychology, 2018
Play during early life is a ubiquitous activity, and an individual’s propensity for play is positively related to cognitive development and emotional well-being.
Dave Neale   +8 more
doaj   +1 more source

From the desk to the cyborg’s faceless interaction in The Norwegian Labour and Welfare Administration

open access: yesNordisk Välfärdsforskning, 2021
We explore the shift from desk to digital services in the Norwegian Labour and Welfare Administration (NAV). This organizational shift is part of the “Channel Strategy”, which aims to route service users through multiple choices of media channel in NAV ...
Ragnhild Fugletveit, Ann-Mari Lofthus
doaj   +1 more source

Social Interactions in Demand [PDF]

open access: yesSSRN Electronic Journal, 2008
We examine theoretically demand in a two-good economy where the demand of one good is influenced by either a spillover effect in the form of an externality from other consumers' choices and or a conformity effect representing a need for making similar choices as others.
Grodner, Andrew, Kniesner, Thomas J
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Lived experiences of migrant men witnessing and surviving sexual violence in European transit spaces

open access: yesGlobalization and Health
Background Despite increased scholarly attention to sexual violence, victimization among migrant men and boys remains under researched. This study aims to explore 1) migrant men’s views on and understandings of sexual victimization, 2) their own ...
Leni Linthout   +4 more
doaj   +1 more source

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