Results 101 to 110 of about 1,489,546 (268)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Lahore Journal of EconomicsWith only half of Pakistan’s rural population provided water through government sources, many observers may well be led to believe that this is a clear case of government failure.
S. Akbar Zaidi
doaj
Perceptions of Ethical and Sustainable Fashion in Japan: A Questionnaire Survey
Journal of Arts, Humanities and Social ScienceEthical and sustainable fashion has attracted increasing attention in discussions of the environmental and social impacts of the fashion-related industry. However, empirical evidence regarding Japanese consumers remains limited.
Kazuki Ide, Atsuo Kishimoto
doaj +1 more source
Big data in social and psychological science: Theoretical and methodological issues
, 2017 Big data presents unprecedented opportunities to understand human behavior on a large scale. It has been increasingly used in social and psychological research to reveal individual differences and group dynamics.
CHAN, Sarah Hian May +5 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Sakarya İletişimYapay zekâ kullanımı birçok sektörde olduğu gibi gazetecilik mesleği ve eğitimi için de önemli bir tartışma konusu haline gelmiştir. İletişim fakültelerinin gazetecilik bölümü öğrencilerinin yapay zekâ kaygı durumlarını tespit etmenin gazetecilik ...
Cengizhan Aynacı +2 more
doaj +1 more source
Leading Issues in Social Media Research
, 2015 Social media is a field of growing importance in our understanding of society, business and education. Emerging from the rapid adoption of internet technologies, social media is liable to grow even more ubiquitous, as the smart phone, tablet and other ...
core