Results 61 to 70 of about 1,489,546 (268)

Doorzetters : een onderzoek naar de betekenis van de arbeidersafkomst voor de levensloop en loopbaan van universitair afgestudeerden

open access: yes, 2010
Go-getters. An inquiry into the Meaning of a Working-class Origin for the Life Course and Career of University Graduates Mick Matthys ‘Go-getters’ discuss the meaning of working class origin for the life and career experiences of university graduates ...
Matthys, M.E.L.   +3 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Social issues infotainment: Using emotion and entertainment to attract readers' attention in social issues leaflets

open access: yes, 2003
Printed leaflets are widely used in social issues campaigns, but there is little evidence to suggest that they are consistently successful and little research to help campaigners decide what techniques will attract audience attention.
Gregory, Judith M.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Adoption Issues [2006]

open access: yes, 2006
application/pdf; Cover title.; "September 28, 2006."; Testimony before the Kansas Legislature, Joint Committee on Children's Issues, by Candy Shively, Deputy Secretary, Kansas Department of Social and Rehabilitation Services.Testimony providing
Shively, Candy.
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Belief and Prediction: Wittgenstein’s Philosophy of Religion in Dialogue with Predictive Processing

open access: yesReligions
The present article aims to offer a new perspective on later Wittgenstein’s notion of belief by comparing the ideas in two well-known works of his, namely, On Certainty (OC) and Philosophical Investigations (PI), with ideas from a widely recognized ...
Nasrin Bani Assadi
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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