Results 21 to 30 of about 1,960,203 (213)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Social Justice Through the Lens of the Cross: A Case for a Biblical Foundation of Social Work [PDF]

, 2019
Social work values social justice, as the profession promotes the well-being of society and the rights each person holds. Although social justice is a core value of social work, it is necessary to address the value’s foundation, and questioning the “why”
Kasch, Allison P
core   +1 more source

The Precursors and Products of Justice Climates: Group Leader Antecedents and Employee Attitudinal Consequences [PDF]

, 2007
Drawing on the organizational justice, organizational climate, leadership and personality, and social comparison theory literatures, we develop hypotheses about the effects of leader personality on the development of three types of justice climates (e.g.,
Adams JS, Avery DR, Bass BM, Bies RJ, Bies RJ, Bies RJ, Bliese PD, Bowen DE, Cohen-Charash Y, Colquitt JA, Costa PT, Costa PT, Cropanzano R, Davis A, De Dreu C., Dietz J, Ehrhart MG., Folger R, Folger R, Folger R., Gelfand MJ, Goldberg LR, Goodstein LD, Greenberg J, Harrison DA, Kirkpatrick SA, Klein KJ, Kozlowski SWJ, Leventhal GS, Lewin K, Lind EA, Lind EA, McGregor D., Mischel W, Naumann SE, Roberson QM, Salvaggio AN, Scandura TA, Schneider B, Shah PS, Singer JD, Spangler WD, Thibaut JW, Tyler TR, van Knippenberg B   +44 more
core   +2 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Liturgy and Social Justice [PDF]

, 1989
(Excerpt) As a prelude to this vast subject, I would like to read a passage which is becoming part of my contemporary canon, a scene from Toni Morrison\u27s novel Beloved.
Lundblad, Barbara K
core   +1 more source

Social Justice in and through Mathematics Education: For Improving the Quality of Mathematics Teaching and Internalising Students’ Character Building [PDF]

, 2020
Aside from being one of the systematically arranged disciplines, mathematics is also a social construction that views humans as active subjects in building knowledge through interaction with the surrounding environment.
., Suhendra, ITOH, Takashi, Nurlaelah, Elah   +2 more
core  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Lawyering for Social Justice [PDF]

, 1997
It is an honor, albeit a sad one, to be invited to write this Essay in commemoration of Tom Stoddard and as commentary on his final publication. I first met Tom in the late 1970s, when we both joined the Board of Directors of the Lambda Legal Defense and
Hunter, Nan D.
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Social media, social justice? Consideration from a career development perspective [PDF]

, 2016
Inside the overall context of careers development, this article will explore how social media relates to social justice through exploring two contrasting perspectives.
Staunton, Tom
core   +2 more sources