Results 111 to 120 of about 1,849,163 (313)

Metadata Creation, Transformation and Discovery for Social Science Data Management: The DAMES Project Infrastructure [PDF]

open access: yes, 2009
This paper discusses the use of metadata, underpinned by DDI (Data Documentation Initiative), to support social science data management. Social science data management refers broadly to the discovery, preparation, and manipulation of social science data ...
Lambert, Paul   +6 more
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

A ADMINISTRAÇÃO PÚBLICA SOCIETAL: um instrumento de controle e participação social

open access: yesRevista de Políticas Públicas, 2018
Post-social states have been glimpsed throughout the world in recent decades. In these states, fundamental rights, such as freedom, gain broader meaning through management models that provide society with eRective forms of parti- cipation.
Marcus Vinicius Gonçalves da Silva   +5 more
doaj  

Corporate social responsibility and management control [PDF]

open access: yes
This paper focuses on the management control processes associated with Corporate Social Responsibility (CSR) issues management in organisations. Following a review of the literature related to management control and CSR, we use a case example of a ...
Alexander Mersereau, Nicolas Mottis
core  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

AVALIAÇÃO DE POLÍTICAS PÚBLICAS: uma análise do programa de volta para casa

open access: yesRevista de Políticas Públicas, 2013
Developed around the theme of politics evaluation of the children and adolescent, the present article has as an objective to introduce the best results found in master degrees research around the theme of partnerships between Government and Non ...
Andréia Cristina Barreto   +1 more
doaj   +2 more sources

Examining recruiters’ assessment of impression management tactics as used by job seekers on social networking sites [PDF]

open access: yes, 2013
Recruiters nowadays have started focusing their attention towards Social Networking Sites (SNS) for they provide an ideal basis to judge one’s personality on, and deal with on-line Impression Management (IM) tactics among job seekers and/or candidates in
Bondarouk, Tanya   +2 more
core  

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

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