Results 81 to 90 of about 20,486,303 (303)
Managing Social Research [PDF]
, 2006 An essential tool for those planning to undertake social research, this exceptional book tackles many of the specific concerns and issues that arise. A well structured text, it offers a comprehensive introduction to a range of important areas in project management, including: commissioning research preparing a tender or grant application risk and ...
openaire +3 more sources
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
MODEL DEVELOPMENT FOR INNOVATION-ORIENTED ENTERPRISE MANAGEMENT
Advanced Engineering Research, 2012 Basic contradictions of the postindustrial period and the strategic and innovation management are r e vealed. The recommendations on the model improvement for the innovation - orie nted enterprise social management are form ulated.
Alexey V., Panfilov
doaj
Saúde e Sociedade, 1999 O que está se tornando evidente, já não numa visão estreita de crítica sistemática anti-capitalista, mas de bom senso econômico e social, é que um sistema que sabe produzir, mas não sabe distribuir, simplesmente não é suficiente.
Ladislau Dowbor
doaj +1 more source
Topologies of power in China's grid-style social management during the COVID-19 pandemic. [PDF]
Secur Dialogue, 2023 Habich-Sobiegalla S, Plümmer F.
europepmc +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Does Computer Use Improve Older Adults' Cognitive Functioning? Evidence From the Personal Reminder Information and Social Management Trial. [PDF]
Gerontologist, 2022 Zhang S, Boot WR, Charness N.
europepmc +1 more source