Results 111 to 120 of about 6,321,139 (306)

Enhancement of urban pluvial flood risk management and resilience through collaborative modelling: a UK case study [PDF]

open access: yes, 2011
This paper presents the main findings and lessons learned from the development and implementation of a new methodology for collaborative modelling, social learning and social acceptance of flood risk management technologies.
Almoradie, A   +12 more
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

SOCIAL PESPONSIBILITY OF THE MODERN MANAGEMENT

open access: yesRussian Journal of Economics and Law, 2007
The article views the issues of the modern social policy formation at the large industrial enterprise and the main means of their solution. The major tool of social management, according to the author, should be the collective agreement.
S. L. Batin
doaj  

Social protection as social risk management : conceptual underpinnings for the social protection sector strategy paper [PDF]

open access: yes
This report serves as a conceptual background piece for the development of the Social Strategy Paper (SSP). To develop the conceptual underpinnings, the objectives and instruments of strategy papers (SP) are viewed under the rubric of Social Risk ...
Holzmann, Robert, Jorgensen, Steen
core  

Seasonal Climate Forecasts and Risk Management Among Georgia Farmers [PDF]

open access: yes, 2008
Recent increases in the scientific robustness of seasonal climate forecasts have not led to substantial changes in farmers’ risk management strategies of actors, largely because there is poor integration of scientific forecasting into farmers’ decision ...
Breuer, N.E.   +6 more
core   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Social Communication in Event Management: Concept and Implementation

open access: yesВестник Кемеровского государственного университета. Серия: политические, социологические и экономические науки
Special events provide organizations with an opportunity to communicate with their prospective customers: private businesses increase brand awareness and loyalty while state socio-cultural institutions pursue various social goals.
Victoria A. Shelginskaya
doaj   +1 more source

Sustainable management: a strategic challenge for a global minerals and metals industry

open access: yes, 2010
This paper refers to the concept of sustainable management as the management approach which efficiently integrates economic, environmental and social issues into the operations of the minerals and metals industries, with the aim of creating long-term ...
Botin Gonzalez, Jose Antonio   +1 more
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

MODEL DEVELOPMENT FOR INNOVATION-ORIENTED ENTERPRISE MANAGEMENT

open access: yesAdvanced Engineering Research, 2012
Basic contradictions of the postindustrial period and the strategic and innovation management are r e vealed. The recommendations on the model improvement for the innovation - orie nted enterprise social management are form ulated.
Alexey V., Panfilov
doaj  

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