Results 91 to 100 of about 20,051,300 (204)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

EARNINGS MANAGEMENT AND CORPORATE SOCIAL RESPONSIBILITY [PDF]

open access: yes
Drawing on stakeholder-agency theory and the earnings management framework, we explore the relationship between discretionary accounting accruals and corporate social responsibility.
Jordi Surroca   +2 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The impact of humor on teachers’ classroom management practice: scoping review of qualitative and quantitative evidence

open access: yesCogent Education
Background Humor is widely recognized as a classroom resource, yet its role in teachers’ management practices remains underexplored.Purpose This scoping review synthesizes existing research to clarify the role of humor in classroom management and ...
Martin Stokke
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

The organization's social environment

open access: yesИзвестия высших учебных заведений: Социология. Экономика. Политика
Several factors contributed to the importance of the study of social environment. These factors include enhancing employee motivation, reducing turnover, and retaining valuable staff; increasing customer and companies-partners loyalty; practical effects ...
A. L. Skifskaya, A. S. Gyurdzhinyan
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Gestão Municipal da Política Nacional de Habitação de Interesse Social. O Trabalho Técnico Social na Gestão de Projetos Habitacionais em Assentamentos Precários em Ananindeua, Estado do Pará

open access: yesDesenvolvimento em Questão, 2016
The paper aims to analyze the Social Technical Work (Trabalho Técnico Social TTS) contribution in housing projects management for precarious settlements. It takes into account the municipality of Ananindeua, Pará state.
Mário Vasconcellos Sobrinho   +2 more
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Landscape management innovations in Ghana by CGIAR and IWMI

open access: yes, 2023
Most social-ecological landscapes are under threat due to poor resource management compounded by the impacts of climate change. The international Water Management Institute (IWMI) employs an inclusive landscape management approach for scaling innovations
International Water Management Institute
core   +1 more source

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