Results 71 to 80 of about 1,215,126 (265)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Programas Sociais Corporativos e Capital Social: Proposta de Qualificação [PDF]
RAC: Revista de Administração Contemporânea, 2010 There is a discourse that has already spread in the social imaginary that identifies the company as the best qualified actor for solving social problems, given their competence when it comes to facing the globalized and competitive market.
Janaina Macke +2 more
doaj
How Do We Measure Social Management in Non-profit Organizations? A Scale Design Based on the Once Case. [PDF]
Front Psychol, 2021 Moreno-Albarracín AL +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
An interactive e-learning module to promote bio-psycho-social management of low back pain in healthcare professionals: a pilot study. [PDF]
J Man Manip Ther, 2022 Fourré A +5 more
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Assistive Robots for the Social Management of Health: A Framework for Robot Design and Human-Robot Interaction Research. [PDF]
Int J Soc Robot, 2021 Chita-Tegmark M, Scheutz M.
europepmc +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Compreensões Acerca do Conceito de Controle Social
Desenvolvimento em Questão, 2017 It is known that there are numerous conceptualizations and several applications of "Social Control" which take into consideration several factors in the world, in this study it was decided to develop a conceptual systematization of the different ...
Fernanda Rodrigues da Silva +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source