Results 61 to 70 of about 1,215,126 (265)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

MODEL DEVELOPMENT FOR INNOVATION-ORIENTED ENTERPRISE MANAGEMENT

open access: yesAdvanced Engineering Research, 2012
Basic contradictions of the postindustrial period and the strategic and innovation management are r e vealed. The recommendations on the model improvement for the innovation - orie nted enterprise social management are form ulated.
Alexey V., Panfilov
doaj  

Emotional intelligence in management activities аnd artificial intelligence technologies

open access: yesЦифровая социология
The article examines the role of emotional intelligence (emotional quotient) in the process of management activities and the competing position of artificial intelligence (hereinafter referred to as AI), which is trying to master it through learning ...
M. S. Laschenov   +2 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

СОЦИАЛЬНЫЕ СТАНДАРТЫ КАЧЕСТВА ЖИЗНИ В СИСТЕМЕ УПРАВЛЕНИЯ СОЦИАЛЬНЫМ РАЗВИТИЕМ СТРАНЫ

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2015
Совершенствование управления социальной сферой, повышение качества жизни российского общества и создание эффективного государства обуславливают необходимость разработки теоретико-методологических подходов к исследованию системы социальных стандартов.
Elena Irekovna Beglova
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

HUMANIZING OF ADMINISTRATIVE ACTIVITY

open access: yesНаучный вестник МГТУ ГА, 2016
The article deals with determining the basic directions of humanizing the administrative activity in organization the content of which provides a constructive dialog in the «leader-subordinate» system based on taking into account of many-sided nature of ...
O. D. Garanina, A. A. Fedyashov
doaj  

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