Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
MODEL DEVELOPMENT FOR INNOVATION-ORIENTED ENTERPRISE MANAGEMENT
Advanced Engineering Research, 2012 Basic contradictions of the postindustrial period and the strategic and innovation management are r e vealed. The recommendations on the model improvement for the innovation - orie nted enterprise social management are form ulated.
Alexey V., Panfilov
doaj
Saúde e Sociedade, 1999 O que está se tornando evidente, já não numa visão estreita de crítica sistemática anti-capitalista, mas de bom senso econômico e social, é que um sistema que sabe produzir, mas não sabe distribuir, simplesmente não é suficiente.
Ladislau Dowbor
doaj +1 more source
Does Computer Use Improve Older Adults' Cognitive Functioning? Evidence From the Personal Reminder Information and Social Management Trial. [PDF]
Gerontologist, 2022 Zhang S, Boot WR, Charness N.
europepmc +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Corporate Social Responsibility and Human Resource Management : A Diversity Perspective
, 2014 This book analyses the intersection between the fields of Corporate Social Responsibility (CSR) and Human Resource Management (HRM), with a focus on diversity management.
core +3 more sources
How Do We Measure Social Management in Non-profit Organizations? A Scale Design Based on the Once Case. [PDF]
Front Psychol, 2021 Moreno-Albarracín AL +3 more
europepmc +1 more source
Corporate social responsibility and management control [PDF]
This paper focuses on the management control processes associated with Corporate Social Responsibility (CSR) issues management in organisations. Following a review of the literature related to management control and CSR, we use a case example of a ...
Alexander Mersereau, Nicolas Mottis
core
Metadata Creation, Transformation and Discovery for Social Science Data Management: The DAMES Project Infrastructure [PDF]
, 2009 This paper discusses the use of metadata, underpinned by DDI (Data Documentation Initiative), to support social science data management. Social science data management refers broadly to the discovery, preparation, and manipulation of social science data ...
Lambert, Paul +6 more
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source