Results 101 to 110 of about 1,249,912 (315)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

AVALIAÇÃO DE POLÍTICAS PÚBLICAS: uma análise do programa de volta para casa

open access: yesRevista de Políticas Públicas, 2013
Developed around the theme of politics evaluation of the children and adolescent, the present article has as an objective to introduce the best results found in master degrees research around the theme of partnerships between Government and Non ...
Andréia Cristina Barreto   +1 more
doaj   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

GESTAo DE pOLíTICA PÚBLICA DE GERACAO DE TRABALHO E RENDA: uma análise do programa nacional de incubadoras de cooperativas populares

open access: yesRevista de Políticas Públicas, 2013
This work aims to identify and analyze the main characteristics of the conduction undertaken management form the "National Program 01 Popular Cooperative Incubators" (Proninc - Programa Nacional de Incubadoras de Cooperativas Populares).
Elisangela Abreu Natividade   +2 more
doaj  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

A ADMINISTRAÇÃO PÚBLICA SOCIETAL: um instrumento de controle e participação social

open access: yesRevista de Políticas Públicas, 2018
Post-social states have been glimpsed throughout the world in recent decades. In these states, fundamental rights, such as freedom, gain broader meaning through management models that provide society with eRective forms of parti- cipation.
Marcus Vinicius Gonçalves da Silva   +5 more
doaj  

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