Results 121 to 130 of about 20,486,303 (303)

Social enterprise: theoretical basis and perespectives [PDF]

open access: yesИкономика и компютърни науки, 2017
Since the 1980s the issues of social enterprises have gained particular popularity, practical and applied, as well as scientific significance. For a short period of time - almost half a century - social enterprises have become an integral part of ...
Julian Narlev
doaj  

The standard for organizational project management (OPM)

open access: yes, 2018
The Standard for Organizational Project Management (OPM) provides a framework and integrated approach using portfolio, program, and project management to deliver organizational strategy for better performance, better results, and a sustainable ...
Project Management Institute
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Management and leadership in social work

open access: yes, 2011
The need for effective management and leadership in social work services is paramount. The demands placed on social work managers to deliver are significant, particularly so for those new to the role.
Mcpheat, Graham, Watson, Joan
core   +2 more sources

GESTAo DE pOLíTICA PÚBLICA DE GERACAO DE TRABALHO E RENDA: uma análise do programa nacional de incubadoras de cooperativas populares

open access: yesRevista de Políticas Públicas, 2013
This work aims to identify and analyze the main characteristics of the conduction undertaken management form the "National Program 01 Popular Cooperative Incubators" (Proninc - Programa Nacional de Incubadoras de Cooperativas Populares).
Elisangela Abreu Natividade   +2 more
doaj  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

A ADMINISTRAÇÃO PÚBLICA SOCIETAL: um instrumento de controle e participação social

open access: yesRevista de Políticas Públicas, 2018
Post-social states have been glimpsed throughout the world in recent decades. In these states, fundamental rights, such as freedom, gain broader meaning through management models that provide society with eRective forms of parti- cipation.
Marcus Vinicius Gonçalves da Silva   +5 more
doaj  

A Social Science Data Fusion Tool and the Data Management through e-Social Science (DAMES) Infrastructure

open access: yes, 2010
The last two decades have seen substantially increased potential for quantitative social science research. This has been made possible by the significant expansion of publicly available social science datasets, the development of new analysis ...
Jones, Simon   +15 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

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