Results 81 to 90 of about 1,215,126 (265)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Social enterprise: theoretical basis and perespectives [PDF]

open access: yesИкономика и компютърни науки, 2017
Since the 1980s the issues of social enterprises have gained particular popularity, practical and applied, as well as scientific significance. For a short period of time - almost half a century - social enterprises have become an integral part of ...
Julian Narlev
doaj  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Gestão Municipal da Política Nacional de Habitação de Interesse Social. O Trabalho Técnico Social na Gestão de Projetos Habitacionais em Assentamentos Precários em Ananindeua, Estado do Pará

open access: yesDesenvolvimento em Questão, 2016
The paper aims to analyze the Social Technical Work (Trabalho Técnico Social TTS) contribution in housing projects management for precarious settlements. It takes into account the municipality of Ananindeua, Pará state.
Mário Vasconcellos Sobrinho   +2 more
doaj  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

AVALIAÇÃO DE POLÍTICAS PÚBLICAS: uma análise do programa de volta para casa

open access: yesRevista de Políticas Públicas, 2013
Developed around the theme of politics evaluation of the children and adolescent, the present article has as an objective to introduce the best results found in master degrees research around the theme of partnerships between Government and Non ...
Andréia Cristina Barreto   +1 more
doaj   +2 more sources

Os Conselhos Municipais de Políticas Públicas sob o Olhar da Comunidade: Uma Experiência de Extensão Universitária

open access: yesDesenvolvimento em Questão, 2012
Based on the relationship between social management and university extension in a freiriana perspective, this article intends to analyze an extension initiative while an instrument for the awareness of the community concerning the importance of the ...
Thais Soares Kronemberger   +3 more
doaj  

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