Results 61 to 70 of about 1,849,163 (313)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Build A Strong Brand Image in Waste Management Social Enterprises

, 2021
Social enterprises of waste management have been growing rapidly overtime. During the pandemic, this sector has become one of the resilient businesses where enterprises should be able to attract attention and become on top of mind with a good perception ...
Rudito, Bambang; School of Business and Management, Institut Teknologi Bandung, Dhita, Tiara Alunan; School of Business and Management, Institut Teknologi Bandung   +1 more
core   +1 more source

MODEL DEVELOPMENT FOR INNOVATION-ORIENTED ENTERPRISE MANAGEMENT

Вестник Донского государственного технического университета, 2018
Basic contradictions of the postindustrial period and the strategic and innovation management are r e vealed. The recommendations on the model improvement for the innovation - orie nted enterprise social management are form ulated.
Alexey V., Panfilov
doaj  

Modern information policy: regional projection

Современная наука и инновации
The present article examines modern approaches to the characterization of the information policy of the Russian Federation and its regional implementation in the Chechen Republic.
A. M. Dudaev, I. V. Kryuchkov
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The Office’s Priorities in the Social Sphere in the Conditions of Transformation of Social Processes

Управленческое консультирование, 2018
The social sector includes all industries and organizations. It performs the basic function of realization of social needs and public services, creating conditions for their livelihoods.
Anatoly Vladimirovich Klyuev
doaj   +1 more source

Conflict Management in Social Work

American Journal of Biomedical Science & Research, 2023
This study aims to determine conflict management principles to eliminate possible conflicts that may arise in the performance of social work functions. As a result of the study, the 2SIP (Socio-Psychological-Social-Implementation-Institutional-PoliticalProfessional) principle was determined for the conflict management of social work. It is thought that
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

The impact of humor on teachers’ classroom management practice: scoping review of qualitative and quantitative evidence

Cogent Education
Background Humor is widely recognized as a classroom resource, yet its role in teachers’ management practices remains underexplored.Purpose This scoping review synthesizes existing research to clarify the role of humor in classroom management and ...
Martin Stokke
doaj   +1 more source

Transition and Metaphor: Crossing a Bridge from Direct Practice to First Line Management in Social Services

, 2015
Moving from direct practice into first line management in social services is a common transition. It is not a trivial change of role however and evokes challenges on both a personal and professional level.
Patterson, Frances
core   +1 more source