Results 81 to 90 of about 20,479,279 (303)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance
Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah +5 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Saúde e Sociedade, 1999 O que está se tornando evidente, já não numa visão estreita de crítica sistemática anti-capitalista, mas de bom senso econômico e social, é que um sistema que sabe produzir, mas não sabe distribuir, simplesmente não é suficiente.
Ladislau Dowbor
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
MODEL DEVELOPMENT FOR INNOVATION-ORIENTED ENTERPRISE MANAGEMENT
Advanced Engineering Research, 2012 Basic contradictions of the postindustrial period and the strategic and innovation management are r e vealed. The recommendations on the model improvement for the innovation - orie nted enterprise social management are form ulated.
Alexey V., Panfilov
doaj
Emotional intelligence in management activities аnd artificial intelligence technologies
Цифровая социологияThe article examines the role of emotional intelligence (emotional quotient) in the process of management activities and the competing position of artificial intelligence (hereinafter referred to as AI), which is trying to master it through learning ...
M. S. Laschenov +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Topologies of power in China's grid-style social management during the COVID-19 pandemic. [PDF]
Secur Dialogue, 2023 Habich-Sobiegalla S, Plümmer F.
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source