Results 121 to 130 of about 21,596,592 (299)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Gestão Municipal da Política Nacional de Habitação de Interesse Social. O Trabalho Técnico Social na Gestão de Projetos Habitacionais em Assentamentos Precários em Ananindeua, Estado do Pará

open access: yesDesenvolvimento em Questão, 2016
The paper aims to analyze the Social Technical Work (Trabalho Técnico Social TTS) contribution in housing projects management for precarious settlements. It takes into account the municipality of Ananindeua, Pará state.
Mário Vasconcellos Sobrinho   +2 more
doaj  

Build A Strong Brand Image in Waste Management Social Enterprises

open access: yes, 2021
Social enterprises of waste management have been growing rapidly overtime. During the pandemic, this sector has become one of the resilient businesses where enterprises should be able to attract attention and become on top of mind with a good perception ...
Rudito, Bambang; School of Business and Management, Institut Teknologi Bandung   +1 more
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Social enterprise: theoretical basis and perespectives [PDF]

open access: yesИкономика и компютърни науки, 2017
Since the 1980s the issues of social enterprises have gained particular popularity, practical and applied, as well as scientific significance. For a short period of time - almost half a century - social enterprises have become an integral part of ...
Julian Narlev
doaj  

Environmental management of social dilemas

open access: yesEuropean Spatial Research and Policy, 1995
Social dilemmas are contradictions between the interests of individuals and the collective interests as expressed in plans and policy proposals. It is argued in this paper that if these social dilemmas are denied in environmental planning then this may have detrimental consequences in the long run for urban ecology and society.
openaire   +3 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

GESTAo DE pOLíTICA PÚBLICA DE GERACAO DE TRABALHO E RENDA: uma análise do programa nacional de incubadoras de cooperativas populares

open access: yesRevista de Políticas Públicas, 2013
This work aims to identify and analyze the main characteristics of the conduction undertaken management form the "National Program 01 Popular Cooperative Incubators" (Proninc - Programa Nacional de Incubadoras de Cooperativas Populares).
Elisangela Abreu Natividade   +2 more
doaj  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

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