Results 131 to 140 of about 21,596,592 (299)
A ADMINISTRAÇÃO PÚBLICA SOCIETAL: um instrumento de controle e participação social
Revista de Políticas Públicas, 2018 Post-social states have been glimpsed throughout the world in recent decades. In these states, fundamental rights, such as freedom, gain broader meaning through management models that provide society with eRective forms of parti- cipation.
Marcus Vinicius Gonçalves da Silva +5 more
doaj
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Landscape management innovations in Ghana by CGIAR and IWMI
, 2023 Most social-ecological landscapes are under threat due to poor resource management compounded by the impacts of climate change. The international Water Management Institute (IWMI) employs an inclusive landscape management approach for scaling innovations
International Water Management Institute
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Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Neoliberal management of social work in Sweden
, 2018 The neo-liberal shift in the Swedish welfare system has entailed different types of power regimes operating through human bodies – through constant processes of surveillance and discipline, including measurement and documentation.
Herz, Marcus, Lalander, Philip
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Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Succession planning : developing management potential in a social services department [PDF]
, 2006 This paper describes a best-practice initiative designed to develop management potential in a local authority social services department. Entitled 'the aspiring managers' programme', it aimed to assist the department with its succession planning using ...
Chick, Neil, Hafford-Letchfield, Trish
core +1 more source
The standard for portfolio management
, 2017 The Standard for Portfolio Management – Fourth Edition has been updated to best reflect the current state of portfolio management. It describe the principles that drive accepted good portfolio management practices in today’s organizations.
Project Management Institute +1 more
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