Deplatforming: Following extreme Internet celebrities to Telegram and alternative social media
Extreme, anti-establishment actors are being characterized increasingly as ‘dangerous individuals’ by the social media platforms that once aided in making them into ‘Internet celebrities’. These individuals (and sometimes groups) are being ‘deplatformed’
Richard Rogers
semanticscholar +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura+8 more
wiley +1 more source
Leveraging Social Foci for Information Seeking in Social Media [PDF]
The rise of social media provides a great opportunity for people to reach out to their social connections to satisfy their information needs. However, generic social media platforms are not explicitly designed to assist information seeking of users.
Hu, Xia+4 more
core +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri+5 more
wiley +1 more source
The Association between Use of Online Social Networks to Find Sex Partners and Sexually Transmitted Infection Diagnosis among Young Men Who Have Sex with Men and Transgender Women Living with HIV. [PDF]
We conducted a cross-sectional analysis of baseline data from the Adolescent Trials Network for HIV/AIDS Interventions to examine the association between the use of social media sites to find sex partners and recent diagnosis of sexually transmitted ...
Hightow-Weidman, Lisa+4 more
core +2 more sources
Social media and vaccine hesitancy
Background Understanding the threat posed by anti-vaccination efforts on social media is critically important with the forth coming need for world wide COVID-19 vaccination programs.
S. Wilson, C. Wiysonge
semanticscholar +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin+2 more
wiley +1 more source
Empowering protest through social media [PDF]
Advances in personal communications devices including smartphones, are enabling individuals to establish and form virtual communities in cyberspace. Such platforms now allow users to be in continuous contact, enabling them to receive information in real ...
O\u27Rourke, Simon
core +1 more source
Exploring the role of social media in collaborative learning the new domain of learning
This study is an attempt to examine the application and usefulness of social media and mobile devices in transferring the resources and interaction with academicians in higher education institutions across the boundary wall, a hitherto unexplained area ...
Jamal Abdul Nasir Ansari, N. Khan
semanticscholar +1 more source
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz+5 more
wiley +1 more source