Results 141 to 150 of about 28,651,409 (314)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Fall 2013 - Deconstructing Social Media

, 2014
Deconstructing Social and Digital Media - Notes, Script, LectureA PDF file of the PowerPoint presentation for the lesson "Deconstructing Social Media."The Feed -- Feed Instructions.pdf The 48-Hour News Blackout -- 48-Hour News Blackout.pdf Censorship --
Stony Brook University. School of Journalism. Center for News Literacy.
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Impact of Social Media Visuals on People’s Visual Communication during Social Movements in Bangladesh

, 2019
The past decade has seen an armorial growth of the influence of social media on many aspects of people s lives Social networking sites especially Facebook play a substantial role in framing popular view through its contents This article explores ...
Shaolin Shaon, MD Saiful Alam Chowdhury, Monira Begum   +2 more
core  

Social Media Usage and Statistics

, 2023
reservedI social media hanno acquisito una posizione di grande rilevanza nella vita quotidiana di tutte le persone. Sono utilizzati per interagire con le persone che ci interessano, ma hanno anche altre funzioni che sono state rese possibili dall ...
LI, CHAO LONG
core  

The Use of Social Media by UK Local Resilience Forums [PDF]

, 2014
The potential uses of social media in the field of emergency preparedness, resilience and response (EPRR) are varied and interesting. The UK government have produced guidance documents for its use in the UK EPRR field but evidence of use is poorly ...
Meaton, Julia, Stringer, Lisa
core   +2 more sources

The effect of social media engagement on social integration of elderly migrants in China: the mechanism of perceived social support and psychological resilience

Humanities & Social Sciences Communications
Surging numbers of older parents have migrated with adult children to developed urban areas under China’s internal family migration, experiencing several difficulties in social integration in local society.
Liu He, Hamedi Bin Mohd Adnan, Ali Fauzi, Muhamad Shamsul Bin Ibrahim   +3 more
doaj   +1 more source

The use of video games and issues of aggressive behavior among pre-adolescent students

Ψυχολογία: το Περιοδικό της Ελληνικής Ψυχολογικής Εταιρείας
The aim of this research is to investigate the relationship between the use of video games and aggressive behavior among students of the fifth and the sixth grade of primary school. The sample consisted of 225 students.
Μαρία Τζιβάνη, Αγγελική Γαζή   +1 more
doaj   +1 more source