Results 41 to 50 of about 95,442 (218)

Effects of antivaccine tweets on COVID-19 vaccinations, cases, and deaths

open access: yesEPJ Data Science
Despite the wide availability of COVID-19 vaccines in the United States and their effectiveness in reducing hospitalizations and mortality during the pandemic, a majority of Americans chose not to be vaccinated during 2021. Recent work shows that vaccine
John Bollenbacher   +2 more
doaj   +1 more source

Jealousy 4.0? An empirical study on jealousy-related discomfort of women evoked by other women and gynoid robots

open access: yesPaladyn, 2018
While first empirical studies on sexual aspects of human-robot interaction mostly focus on male users’ acceptance, there is no empirical research on how females react to robotic replications of women.
Szczuka Jessica M., Krämer Nicole C.
doaj   +1 more source

Let the Weakest Link Go! Empirical Explorations on the Relative Importance of Weak and Strong Ties on Social Networking Sites

open access: yesSocieties, 2014
Theoretical approaches as well as empirical results in the area of social capital accumulation on social networking sites suggest that weak ties/bridging versus strong ties/bonding social capital should be distinguished and that while bonding social ...
Nicole C. Krämer   +4 more
doaj   +1 more source

Social Media Research Network: Social Media Toolkit

open access: yes, 2021
The Social Media Research Network was co-founded by Chantelle Roulston and Akash Shroff in August 2021 with the support of Dr. Jessica Schleider and the Lab for Scalable Mental Health (LSMH). Since 2018, LSMH has been recruiting adolescents and parents using social media—primarily Facebook and Instagram.
Akash Shroff   +3 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Two-Study Approach to Explore the Effect of User Characteristics on Users’ Perception and Evaluation of a Virtual Assistant’s Appearance

open access: yesMultimodal Technologies and Interaction, 2018
This research investigates the effect of different user characteristics on the perception and evaluation of an agent’s appearance variables. Therefore, two different experiments have been conducted. In a 3 × 3 × 5 within-subjects design
Carolin Straßmann, Nicole C. Krämer
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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