Results 101 to 110 of about 777,898 (310)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Understanding e-WOM evolution in social media with network analysis

, 2021
Today's consumer is in constant interaction with the environment thanks to social media and technology. Consumers who communicate more with each other have pushed businesses to take action on this issue.
Pınarbaşı, Fatih
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Social Media Analysis for Effective Information Dissemination and Promotions Using TOPSIS

Journal of Applied Informatics and Computing
Social media has become an essential tool for spreading news and promotions. This research aims to evaluate the effectiveness of using social media as a strategy for disseminating information and promoting products using the TOPSIS method.
Reka Hani Latifah Nurhasanah, Abdul Halim Anshor, Asep Muhidin   +2 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Sentiment analysis and opinion mining from social media: A review [PDF]

, 2016
Ubiquitous presence of internet, advent of web 2.0 has made social media tools like blogs, Facebook, Twitter very popular and effective. People interact with each other, share their ideas, opinions, interests and personal information. These user comments
Savitha Mathapati, ., Manjula, S.H., Venugopal, K.R.   +2 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Sentiment analysis of post-COVID-19 health information needs of autism spectrum disorder community: insights from social media discussions

Frontiers in Psychiatry
ObjectiveThis study explores the health information needs of individuals with autism spectrum disorder (ASD) and their caregivers in the post-COVID-19 era by analyzing discussions from Reddit, a popular social media platform.MethodsUtilizing a mixed ...
Ebenezer Larnyo, Jonathan Aseye Nutakor, Stephen Addai-Dansoh, Edmund Nana Kwame Nkrumah   +3 more
doaj   +1 more source

Emotion Detection and Analysis on Social Media

CoRR, 2019
In this paper, we address the problem of detection, classification and quantification of emotions of text in any form. We consider English text collected from social media like Twitter, which can provide information having utility in a variety of ways, especially opinion mining.
Bharat Gaind, Varun Syal, Sneha Padgalwar   +2 more
openaire   +2 more sources

Social media for people with a disability

, 2016
Social media allows anyone with internet access to connect with other people and publish their own content. Through it, we receive a wealth of information and interaction that allows us to keep up important relationships and get things done.
Media Access Australia
core