Results 121 to 130 of about 881,130 (297)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Updating the Social Network: How Outdated and Unclear State Legislation Violates Sex Offenders’ First Amendment Rights [PDF]
, 2017 Readily available on computers, phones, tablets, or television, social media has become a necessary platform of expression for many. But, for others, social media is an inaccessible tool whose very use has criminal repercussions.
Tolon, Elizabeth
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
IMPACTS OF SOCIAL MEDIA TOWARDS LANGUAGE SHIFT AMONG UNIVERSITY STUDENTS [PDF]
, 2015 Social Media Applications are inevitable in today’s people’s lives, especially for university students who cannot be separated with their gadgets. It is undeniable that the use of social media changes the way people communicate with each other, from ...
Karjo, Clara Herlina
core
Social Media Usage Behavior Aimed at Improving the Quality of Life of the Elderly in Roi Et Province
Journal of Humanities and Social Sciences Mahasarakham UniversityThis study was quantitative research, investigating the relationship and the difference of social media usage behavior for improving the quality-of-life of the elderly in Roi Et Province.
Sutanya Krittakom
doaj
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Enabling Mobile Communications for the Needy: Affordability Methodology, and Approaches to Requalify Universal Service Measures [PDF]
This paper links communications and media usage to social and household economics boundaries. It highlights that in present day society, communications and media are a necessity, but not always affordable, and that they furthermore open up for addictive ...
Louis-Francois PAU
core
From a Global Perspective, Based on Cost‐Benefit Analysis, Which Social Media Tool(s) is/are the Most Effective for Attracting Talent? [PDF]
, 2014 Social media usage has been growing quite impressively in the last few years, and it has penetrated the recruiting market almost entirely: the number of companies using social media to support their recruitment efforts has gone from 78% in 2008 to 92% in
Ameisen, Emmanuel, Balter, Roscoe
core +1 more source
Using Social Media to Promote STEM Education: Matching College Students with Role Models
, 2016 STEM (Science, Technology, Engineering, and Mathematics) fields have become increasingly central to U.S. economic competitiveness and growth. The shortage in the STEM workforce has brought promoting STEM education upfront.
A Bandura +18 more
core +1 more source