Results 51 to 60 of about 881,130 (297)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Asian Government Usage of Web 2.0 Social Media [PDF]

open access: yes, 2010
The rise of Web 2.0 social sites, such as Facebook, Twitter and YouTube has brought significant changes and opportunities for both online consumers and governments.
Kuzma, Joanne
core   +1 more source

A study on social media usage and fear of missing out (FOMO) among youngsters [PDF]

open access: yesJournal of Studies in Social Sciences and Humanities, 2020
The rapid growth of social media platform has led to evolve communal distress regarding the way in teenagers and young adults have engaged themselves in the verge of destruction.
Prerna Gosain Student - M.A. Psychology, Email: prernagk2218@gmail.com   +1 more
doaj  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Comparison of Public Relations and News Professionals’ Usage of Social Media in Communication Relationships [PDF]

open access: yes, 2011
Professionals in the areas of public relations and news adopt social media extensively in their respective disciplines. Thus the focus of this study is to ascertain how social media was used in professional communication.
Stalbaum, Kathy
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Social media usage in academic research [PDF]

open access: yes, 2016
Recently researchers have used “conversation prism” and “social media prisma”, to consolidate social medias with respect to their use. Although both identified 25 types, having average five examples each, they did not identify contribution of each type ...
Ghani, I.   +4 more
core  

Examining Information on Social Media: Topic Modelling, Trend Prediction and Community Classification [PDF]

open access: yes, 2017
In the past decade, the use of social media networks (e.g. Twitter) increased dramatically becoming the main channels for the mass public to express their opinions, ideas and preferences, especially during an election or a referendum.
Fang Anjie, Fang Anjie, Fang Anjie
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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