Results 81 to 90 of about 28,825,798 (236)
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Predicting Product Performance with Social Media [PDF]
Last 20 years brought massive growth in IT&C world. Mobile solutions such as netbooks, laptops, mobile phones, tablets enable the wireless connection to the Internet. Anyone can ac-cess it anytime and anywhere.
Liviu LICA, Mihaela TUTÄ‚
core
The role of social media usage, gratitude, self- esteem, and religiosity on volunteerism among Malaysian youth [PDF]
This study investigates the relationship between social media usage, gratitude, self-esteem, religiosity, and volunteerism among Malaysian youth. The research examines how these key factors—social media usage, gratitude, self-esteem, and religiosity ...
Abdullah, Haslinda +2 more
core +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The Benefits of Social Media Among Children Aged 8 to 17 in Tema Metropolitan Area in Ghana
SAGE OpenIn modern society, children actively engage with social media platforms, and Ghana is not an exception to this trend. People have, however, placed an excessive amount of focus on the negative implications of using social media, which has overshadowed the
Sylvester Kyei-Gyamfi
doaj +1 more source
The impact of the COVID-19 pandemic on the use of social media: A cross-national comparison
Acta PsychologicaThis study investigates the impact of limited interpersonal interaction due to the COVID-19 pandemic on social media usage in the USA and Italy, considering their differences in lockdown restrictions.
Franco Delogu +5 more
doaj +1 more source