Results 161 to 170 of about 3,546,196 (306)

Problematic social media use among recreational cannabis users in Québec: A Cross-Sectional study. [PDF]

Addict Behav Rep
Deli-Houssein R, Hudon C, Dufour I, Carrier N, Gómez NM, Deschamps A, Auger AM, Brodeur M.   +7 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Patient directed social media use among participants of centering pregnancy groups. [PDF]

J Health Popul Nutr
El Ayadi AM, Diamond-Smith NG, Schuman M, Weil L.   +3 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Social Identity, Social Media Use, and Mental Health in Adults: Investigating the Mediating Role of Cyberbullying Experiences and the Moderating Effects of Gender and Age

Psychology Research and Behavior Management
Natali Barragan,1 Amanda Batista,1 Deborah L Hall,1 Yasin N Silva2 1School of Social & Behavioral Sciences, Arizona State University, Glendale, AZ, USA; 2Department of Computer Science, Loyola University Chicago, Chicago, IL, USACorrespondence: Deborah L
Barragan N, Batista A, Hall DL, Silva YN
doaj  

Correction: Problematic social media use and psychological symptoms in adolescents. [PDF]

Soc Psychiatry Psychiatr Epidemiol
Mojtabai R.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The relationships between social media use, time management, and decision-making styles. [PDF]

Front Psychol
Şıngır H.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Editorial: Excessive and problematic smartphone usage, volume II

Frontiers in Psychiatry, 2023
Aviv M. Weinstein, Kristiana Siste
doaj   +1 more source