Results 51 to 60 of about 1,281,195 (288)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Influence of gait-synchronized functional electrical stimulation during exoskeleton-assisted ambulation on cardiorespiratory outcomes in individuals with incomplete spinal cord injury

Journal of Rehabilitation Medicine
Objective: To evaluate the impact of gait-synchronized functional electrical stimulation during exoskeleton-assisted ambulation on cardiorespiratory demand in individuals with incomplete spinal cord injury.
Robert Voicu, Daniela B. Kuchen, Claudio Perret, Ines Bersch, Mario Widmer   +4 more
doaj   +1 more source

Unequal Occupational Mobilities Between Rural Migrant and Urban Resident Workers in Urban China

Frontiers in Sociology, 2020
The current scholarship on inequality of occupational attainment between rural migrant workers (RMW) and urban resident workers (URW) is largely dominated by evidence suggesting a landscape of occupational segregation, whilst there is a lack of studies ...
Chong Zhang
doaj   +1 more source

Welfare Policies and Racial Stereotypes: The Structural Construction of a Model Minority [PDF]

, 1994
Whereas the economic mobility observed among Asian Americans is often attributed to their cultural values, this article demonstrates the importance of state aid to the economic mobility of a community of Southeast Asian refugees living in California ...
Kelsey, Mary E.
core   +2 more sources

Sperm mobility: mechanisms of fertilizing efficiency, genetic variation and phenotypic relationship with male status in the domestic fowl, Gallus gallus domesticus [PDF]

, 2002
When females are sexually promiscuous, sexual selection continues after insemination through sperm competition and cryptic female choice, and male traits conveying an advantage in competitive fertilization are selected for. Although individual male and
Allen J Feltmann, David P Froman, Hector Castillo-Juarez, Pizzari T., Sullivan M. S., Tim R Birkhead, Tommaso Pizzari   +6 more
core   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Association between Chronic Pain and Depression among the Elderly of Amirkola City, Northern Iran

Elderly Health Journal, 2017
Introduction: Chronic pain and depression are two of common geriatric disorders. The aim of this study was to investigate the association between chronic pain and depressive symptoms in older people in Amirkola.   Methods: This cross-sectional study
Alijan Ahmadi Ahangar, Seyed Reza Hosseini, Farzan Kheirkhah, Masoumeh Karimi, Payam Saadat, Ali Bijani, Shayan Alijanpour, Hamed Hosseinzadeh, Sakineh Faraji   +8 more
doaj  

Location Prediction: Communities Speak Louder than Friends [PDF]

, 2015
Humans are social animals, they interact with different communities of friends to conduct different activities. The literature shows that human mobility is constrained by their social relations. In this paper, we investigate the social impact of a person'
Pang, Jun, Zhang, Yang
core   +3 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

‘Talent-spotting’ or ‘social magic’? Inequality, cultural sorting and constructions of the ideal graduate in elite professions [PDF]

, 2018
Graduate outcomes – including rates of employment and earnings – are marked by persistent inequalities related to social class, as well as gender, ethnicity and institution. Despite national policy agendas related to social mobility and ‘fair access to
Bourdieu P., Bourdieu P., Bourdieu P., Britton J., Burke C., Department for Business Innovation and Skills, Friedman S., High Fliers, Higher Education Funding Council for England, Kaputa C., Kim Allen, Meiert J. O., Milburn A., Nicola Ingram, Purcell K., Puwar N., Rose G., Social Mobility and Child Poverty Commission, Social Mobility Commission, Universities UK   +19 more
core   +3 more sources