Results 171 to 180 of about 14,856,832 (359)
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
"I didn't sign up for this!" : informed consent in social network research
, 2015 This work was funded by the Engineering and Physical Sciences Research Council (EPSRC) through a Doctoral Training Grant.The issue of whether, and how, to obtain informed consent for research studies that use social network data has recently come to the ...
Hutton, Luke, Henderson, Tristan
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 2013 Bilecen B. Analyzing Informal Social Protection Across Borders: Synthesizing Social Network Analysis with Qualitative Interviews. SFB 882 Working Paper Series. Vol 19.
Bilecen, Basak
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Poverty Reduction and Social Protection Network
, 2016 This presentation discusses the goals, priorities, and instruments of the Poverty and Social Protection Network, which promotes equitable, integrated and sustainable social policies and programs in the LAC region.
Inter-American Development Bank (IDB) +3 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Email may not reflect the social network. Preliminary Insights
, 2006 Researchers have demonstrated that e-mail archives can be used as a good approximation of social ties (Tyler et. al.). This paper demonstrates that ties obtained by mining e-mails archives do not necessarily provide a complete and realistic approximation
LAUBACHER R +3 more
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Premenstrual dysphoric disorder in online peer support communities: a Reddit case study
Scientific ReportsThe growing reliance on online communities has reshaped how individuals articulate, validate, and navigate psychological distress. However, the value of online peer support spaces remains insufficiently studied, particularly in the context of ...
Bojan Evkoski +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source