Results 71 to 80 of about 39,966 (217)
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
The Social Responsibility of a Social Network
You may have participated in a published research study without even knowing it. In 2012, Facebook ran an experiment on almost 700,000 users wherein their emotions were manipulated without the participants knowing they enrolled in the study. After the paper was published, many users inquired as to when they gave consent to participate in the study ...
openaire +2 more sources
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The evidence base for the use of immersive technologies, such as Virtual Reality (VR), for the treatment of Post-Traumatic Stress Disorder (PTSD) is compelling.
Paul Best +8 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
An Interdisciplinary Concept of Activity
It is suggested that if Cultural-Historical Activity Theory (CHAT) is to fulfil its potential as an approach to cultural and historical science in general, then an interdisciplinary concept of activity is needed.
Andy Blunden
doaj
Work Organization and Professionalization in New Media Industry – The Case of a Finnish Company
The article explores work organization in one new media company in a turning point of the business, in the 2000s. The company had changed from a small workshop to a medium-sized company in a few years.
Arja Haapakorpi
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Social networks: effects and formation
Social networks affect individual behavior as well as social phenomena resulting from behavior ('effects'). Also, when actors can choose with whom to interact, social networks themselves are shaped by behavior ('formation'). This chapter provides a selective overview of rigorous sociology on effects of social networks and their formation.
Buskens, Vincent +2 more
openaire +2 more sources

