Results 71 to 80 of about 17,941,414 (255)

Exercise addiction – the emergence of a new disorder [PDF]

, 2014
An optimal level of regular physical activity plays an important role in the maintenance of physical and mental health. However, excessive exercise in a minority of individuals can have adverse effects on health and lead to exercise addiction.
Demetrovics, Zsolt, Szabó, Attila, Berczik, K, Griffiths, MD, Kökönyei, Gyöngyi, Szabó, A, Kurimay, T, Urbán, R, Kökönyei, G, Urbán, Róbert, Demetrovics, Z, Kurimay, Tamás, Berczik, Krisztina, Griffiths, Mark   +13 more
core  

Reliable online social network data collection [PDF]

, 2012
Large quantities of information are shared through online social networks, making them attractive sources of data for social network research. When studying the usage of online social networks, these data may not describe properly users’ behaviours.
Parris, Iain, Abdesslem, Fehmi Ben, Fehmi Ben Abdesslem, Henderson, Tristan, Iain Parris, Tristan Henderson   +5 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Social marketing, smoking cessation and inequalities

, 2006
First paragraph: 'Social marketing' is gaining currency. It was identified as a key tool in the UK's recent public health White Paper (Choosing Health 2004) and the Canadian, New Zealand, Australian and US governments are all exploring its potential.
Hastings, Gerard, McLean, Neil, NEIL MCLEAN, GERARD HASTINGS   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Addiction, Social Interactions and Gender Differences in Cigarette Consumption [PDF]

This paper addresses the impact of addiction and social interactions on cigarette demand, controlling for demographic and socioeconomic factors. A Box-Cox double-hurdle model for the simultaneous decisions of how much to smoke and whether to quit smoking
David Aristei, Luca Pieroni
core  

Methodological and conceptual limitations in exercise addiction research [PDF]

, 2015
The aim of this brief analytical review is to highlight and disentangle research dilemmas in the field of exercise addiction. Research examining exercise addiction is primarily based on self-reports, obtained by questionnaires (incorporating ...
Demetrovics, Zsolt, Vega Marcosc, Barbara Mervód, Szabó, Attila, Ricardo La, Griffiths, MD, Zsolt Demetrovicsd, Szabo, A, Mervó, B, de La Vega Marcos, R, Mervó, Barbara, Griffiths, Mark D., de la Vega, Ricardo, Demetrovics, Z, Vega Marcos, Ricardo de la, Mark D. Griffithsb, Attila Szaboa   +16 more
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Addiction Phenomenology In Substance Use And Non-Substance Use Disorders [PDF]

, 2008
There is growing research evidence and public concern over the burgeoning of disorders which share common features with substance addictions. In order to investigate the presence and role of addiction features in disorders outside of substance addictions,
McLachlan, Andre David
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source