Results 171 to 180 of about 14,102,468 (353)

USE OF COLLABORATIVE TOOLS AND SOCIAL NETWORKING APPLICATIONS FOR KNOWLEDGE MANAGEMENT INSIDE IT COMPANIES [PDF]

open access: yes
In this paper a presentation is given of how collaborative tools and social networking applications can be used inside IT companies. The field of IT was chosen for its particularities and the particularities of the companies in it.
Liviu LICÃ
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Self-concept and online social networking in young adolescents : implications for school counselors

open access: yes, 2013
textThe current report reviews the recent research on online social networking sites (MySpace and Facebook), and their impact on adolescent self-concept and identity development. This paper describes the history and recent expansion of social networking
Livsey, Brianna Kathleen
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Word is Out: The Use of Social Networking Sites During the Coming Out Process

open access: yes, 2011
WORD IS OUT: THE USE OF SOCIAL NETWORKING SITES\ud DURING THE COMING OUT PROCESS\ud by\ud Rachel Ann Sauerbier\ud Master of Arts in Communication Studies\ud California State University, Chico\ud Spring 2011\ud The purpose of this research was to explore ...
Sauerbier, Rachel Ann
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

See you on Facebook: the effect of social networking on human interaction

open access: yes
This paper proposes an evolutionary framework to explore the dynamics of social interaction in an environment characterized by online networking and increasing pressure on time.
Sabatini, Fabio   +2 more
core  

Science 2.0: The Use of Social Networking in Research [PDF]

open access: yes, 2011
Updated 2011. REBIUN study on Science 2.0 and social web applications for research. There are three categories: share research, share resources and share results.
REBIUN,, REBIUN
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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